DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12173 and SPAC644.08

DIOPT Version :9

Sequence 1:	NP_649523.1	Gene:	CG12173 / 40630	FlyBaseID:	FBgn0037305	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_593876.1	Gene:	SPAC644.08 / 2543661	PomBaseID:	SPAC644.08	Length:	216	Species:	Schizosaccharomyces pombe

Alignment Length:	238	Identity:	91/238 - (38%)
Similarity:	130/238 - (54%)	Gaps:	25/238 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VAKVVLVDIEGTTTSISFVHDVLFPYAKQNVEKFLRDSWEEDDIKRIVQDLQQVPQYADYKALLS 71
            :.|.:|:|||||..|||||.|.|||||....|.::.:::|.|:..|   :|.:.|:    :||::
pombe     1 MVKNLLLDIEGTVGSISFVKDKLFPYAASRYESYVNENYESDENLR---ELGKTPE----EALIN 58

  Fly    72 GPPTEVDVDLIAGFVRYLIDQDLKVTPMKTLQGLIWAQGYANGELKGHVYEDVPAAFEAWRAAGL 136
                          :|.|..:..|....|.:||.||.:||.:.||..|::.||..|.:.....|:
pombe    59 --------------LRKLHAEGSKERSFKMVQGRIWKKGYESNELTSHLFPDVVPAIQRSLQLGM 109

  Fly   137 QIAVYSSGSVAAQKLIFGHSLAGNLQPYLSAYFDTHVGHKQEQQSYKNIAKQLKEDPKQILFLTD 201
            ::.:||||||.||||.|.||.||||..|.|.|:||.:|.|.|..||..|..  ..:|::.|||:|
pombe   110 RVYIYSSGSVPAQKLYFEHSDAGNLLKYFSGYYDTTIGLKTECGSYVKIVG--NSNPREWLFLSD 172

  Fly   202 IPGEAAAARCAGLQAIILKRPGNAALADDQKTGFELIPDFKPL 244
            ...|..|||..||...::.||||..:.|  .:||.:...|:.|
pombe   173 NINELKAARKVGLHTGLVVRPGNDPVVD--TSGFPVYNSFEIL 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12173	NP_649523.1	enolase-ppase	8..244	CDD:273760	90/235 (38%)
CG12173	NP_649523.1	HAD_2	11..217	CDD:290155	81/205 (40%)
SPAC644.08	NP_593876.1	Utr4	1..216	CDD:226682	91/238 (38%)
SPAC644.08	NP_593876.1	HAD_2	5..190	CDD:290155	81/207 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	128	1.000	Domainoid score	I1367
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1366
OMA	1	1.010	-	-		QHG62493
OrthoFinder	1	1.000	-	-		FOG0004317
OrthoInspector	1	1.000	-	-		oto101319
orthoMCL	1	0.900	-	-		OOG6_104759
Panther	1	1.100	-	-	LDO	PTHR20371
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R398
SonicParanoid	1	1.000	-	-		X3051
TreeFam	0	0.000	Not matched by this tool.
	11	11.000