Protein Alignment CG1113 and FAM161A

DIOPT Version :9

• Sequence 1: NP_001262277.1
• Gene: CG1113 / 40629
• FlyBaseID: FBgn0037304
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001188472.1
• Gene: FAM161A / 84140
• HGNCID: 25808
• Length: 716
• Species: Homo sapiens
• Alignment Length: 657
• Identity: 132/657 - (20%)
• Similarity: 232/657 - (35%)
• Gaps: 195/657 - (29%)

  Fly     8 SCVKVPIDPCNNCPAPVYNR-PKLSSLGGK----KPTDQAHISQPE-AETPAWSSQMGVRSLAKF 66
            |.::.|::|........|.| ..|.:|...    :..::..::||. |.....:|..||...|..
Human    13 SSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGASADLNTSFSGVDEHAPI 77

  Fly    67 -YDSIPDYRDVKHLHRVEFYSTLESLRSTSRELRSQAATAPTVERSASVSSCSVGHGKSKKRPSK 130
             |:...::.|:.|.:. |::..:|.|:         ||...|:                    :|
Human    78 SYEDFVNFPDIHHSNE-EYFKKVEELK---------AAHIETM--------------------AK 112

  Fly   131 GKKIKKRPLVLDPVPPPAILVIPGQQDRCATRPVVHTPNSSCLSDEYDQCLRDLSRLKSFKE--- 192
            .:|:.:..|.|..|.|..|     ::|..       :.:|..:|::  .....:|.:.||.|
Human   113 LEKMYQDKLHLKEVQPVVI-----REDSL-------SDSSRSVSEK--NSYHPVSLMTSFSEPDL 163

  Fly   193 --DFAVEVADFKRSLKSFEAEFRRPKSTSSNGTQTQTNKQS----QTQNRCQKTANPGQHTAE-R 250
              ..::.|:..:..|.:.|.|:.|.....:...:...|..:    :...||:.|   |.|.|| |
Human   164 GQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDT---GFHAAEKR 225

  Fly   251 AKCRRE-------------MLRR-------CFSVNDLQGI--ALEAHSKPSKLAQPARSN----- 288
            .|.|:|             |:|.       ..|.:|::.:  ||:...:..:..:..|:|
Human   226 RKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPAS 290

  Fly   289 -----YFPLSKQEEIPKIQIQSPTTSSKRSSSASS-------------AARGRGRRGRVRKPKPG 335
                 |..|.||:|..:   :|....||.:..||.             |||.:..|..::..|..
Human   291 VFLPLYHDLVKQKEERR---RSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKT 352

  Fly   336 SSVKDEKPLPPLSIY------ELPEEPVQRRTPSVSPLHPVSRPNLAATLRAEVSRKKVKEL--K 392
            :..| .:|: |.|.|      :|.||.:.|              ||...|||:...:....|  :
Human   353 NRFK-ARPI-PRSTYGSTTNDKLKEEELYR--------------NLRTQLRAQEHLQNSSPLPCR 401

  Fly   393 NNCTYHDPR----------------PQFDWEVRKTPAWKSLSLNESHKAL-------------LS 428
            :.|...:||                |..|:|.......|.||.::|.|.|             .|
Human   402 SACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHAS 466

  Fly   429 IRLATRKAE-QAFQERQYELHMEMMRQRVKSAPLLLEG----PTFWGPEVGKLTHTCRTEELRHS 488
            |:.....|: :|.:|...|.....:..|.|| |:...|    |....|.|..::...|.:.:|.|
Human   467 IKREKILADIEADEENLKETRWPYLSPRRKS-PVRCAGVNPVPCNCNPPVPTVSSRGREQAVRRS 530

  Fly   489 CEGSRQRRKKKSEFPVPDADTKLQQLRKVYGSEKSCSRQSQRSKRSERRPQGLTTETPSHDSGDD 553
            .|..:...::::                     :..::|.||.|..::.   |||...::||...
Human   531 LEEKKMLEEERN---------------------RILTKQKQRMKELQKL---LTTRAKAYDSHQS 571

  Fly   554 LCSADRA 560
            |....::
Human   572 LAQISKS 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1113	NP_001262277.1	None
FAM161A	NP_001188472.1	UPF0564	234..595	CDD:287553	78/389 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28J06
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003802
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.900