Protein Alignment CG1113 and FAM161B

DIOPT Version :9

• Sequence 1: NP_001262277.1
• Gene: CG1113 / 40629
• FlyBaseID: FBgn0037304
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_011534777.1
• Gene: FAM161B / 145483
• HGNCID: 19854
• Length: 706
• Species: Homo sapiens
• Alignment Length: 721
• Identity: 143/721 - (19%)
• Similarity: 233/721 - (32%)
• Gaps: 258/721 - (35%)

  Fly     4 HYLNSCVKVPIDPCNNCPAPV-YNRPKLSSLGGKKPTDQAHISQPEAETPAWSSQMG-------V 60
            ||...|      .|..|||.: ..||: .:.||.:.:.|....:..|:|.|.....|       .
Human    50 HYRCHC------RCCLCPAEMTVGRPE-GAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRA 107

  Fly    61 RSLAKF------YDSIPD-----YRDVKHLHRVEFYSTLESLRSTSRE-----------LRS--- 100
            ..|.:|      .||..|     |::::.|.:...:..||||..:..|           |.|
Human   108 SKLDEFLSPEEEIDSTSDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQ 172

  Fly   101 ------------QAATAPTVERSASVSSCSVGHGKSKKRPSKGKKIKKRPLVLDPVPPPAILVIP 153
                        ||....:..|.:|:::......:.:.:|..|    .||              |
Human   173 DKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSG----SRP--------------P 219

  Fly   154 GQQDRCATRPVVHTPNSSCLSDEYDQCLRDLSRLKSFKEDFAVEVADFKRSLKSFEAEFRRPKST 218
            .|.     |.|....:|..:...:...||:           |.:.|::..|..|||.|.:|
Human   220 SQH-----RSVSSWASSITVPRPFRMTLRE-----------ARKKAEWLGSPASFEQERQR---- 264

  Fly   219 SSNGTQTQTNKQSQTQNRCQKTANPG-------QHTAERAKCRR--------------------- 255
                .|.|..::::...:.:....|.       |...||::.||
Human   265 ----AQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFL 325

  Fly   256 ---EMLRRCFSVNDLQGIALEAHSK-------PSKLAQPARSNYFPLSKQEEIPKIQIQ------ 304
               |.|:......||...|....||       |..:.:||..:  .|.:.|...||:||
Human   326 EKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGD--KLQEAELFRKIRIQMRALDM 388

  Fly   305 -----SPTTSSKRSSS------------------------------------------------- 315
                 ||..||...::
Human   389 LQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRR 453

  Fly   316 -ASSAARGRG---RRGRVRKP-KPGSSV----KDEKPLPPLSIYELPEEPVQRRTPSVSPLHPVS 371
             ...|.|.:.   |...:|.| :|..:.    :.:.|.||.:  .||      |:.|:|.|..:|
Human   454 ETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPAT--PLP------RSRSLSGLASLS 510

  Fly   372 RPNLA-----ATLRAEVSRKKVKELKNNCTYHDPRPQFDW-EVRKTPAW---KSLSLN----ESH 423
            ...|.     ||.:.|.:.:...|.||...     ....| |:.|..:.   ||::|.    :.|
Human   511 ANTLPVHITDATRKRESAVRSALEKKNKAD-----ESIQWLEIHKKKSQAMSKSVTLRAKAMDPH 570

  Fly   424 KALLSI---RLATRKAEQAFQERQYELHMEMMRQRVKSAPLLLEGPTFWGPEVGKLTHTCRTEE- 484
            |:|..:   :|...:.....:.::|:..:|.|:||:::.|.|.|       :|.|.......|:
Human   571 KSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFE-------QVAKDLAKKEAEQW 628

  Fly   485 ----LRHS-CEGSRQRRKKKSEFPVPDADTKLQQLRKVYGSEKSCSRQSQRSKRSERRP-QGL-- 541
                |:.: .|....|.|.:....|.:.:||:          |...|..:.:|.|.|.| |||
Human   629 YLDTLKQAGLEEDFVRNKGQGTRAVQEKETKI----------KDFPRFQETTKLSIRDPEQGLEG 683

  Fly   542 TTETPS 547
            :.|.|:
Human   684 SLEQPA 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1113	NP_001262277.1	None
FAM161B	XP_011534777.1	UPF0564	230..599	CDD:287553	73/402 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003802
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6399
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.000