DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Tinagl1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_446034.1	Gene:	Tinagl1 / 94174	RGDID:	70956	Length:	467	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	67/256 - (26%)
Similarity:	114/256 - (44%)	Gaps:	49/256 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 GE-LPKEFDWRQK--DAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKT-GELKE-FSEQELLDCDT 451
            || ||..|:..:|  :.:.:..:||:|...||||.........::.: |.:.. .|.|.||.|||
  Rat   199 GEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDT 263

  Fly   452 -TDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKK--------------------------NQC 489
             ....|.||.:|.|:..::..|.:.... ||:..::                          ::|
  Rat   264 HHQKGCRGGRLDGAWWFLRRRGVVSDNC-YPFSGREQNDEASPTPRCMMHSRAMGRGKRQATSRC 327

  Fly   490 HFNRTLSH--VQVAGFVDLPKGNETAMQEWLLANGPIS--IGINANAMQFYRGGVSH-------P 543
            ..::..|:  .||.....|....:..|:| |:.|||:.  :.::.:...:.||..||       |
  Rat   328 PNSQVDSNDIYQVTPVYRLASDEKEIMKE-LMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRP 391

  Fly   544 WKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGV 604
            .:   .:::..|.|.:.|:|....|: .:|:.||...|||||.|||:|::|:.||.|.|.:
  Rat   392 EQ---YRRHGTHSVKITGWGEETLPD-GRTIKYWTAANSWGPWWGERGHFRIVRGINECDI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458
		Peptidase_C1A	395..611	CDD:239068	64/252 (25%)
Tinagl1	NP_446034.1	Somatomedin_B	53..93	CDD:279385
		VWC	104..>152	CDD:302663
		Peptidase_C1A_CathepsinB	203..455	CDD:239111	64/252 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910