DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and RD21A

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_564497.1	Gene:	RD21A / 841122	AraportID:	AT1G47128	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	120/314 - (38%)
Similarity:	179/314 - (57%)	Gaps:	24/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 KVDHLFYKFQVRFGRRYV--STAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEY 365
            :|..::..:.|:.|:...  |..|:..|..||:.||:.::|.|...: |.:.|:|.|||:|:.||
plant    45 EVMSIYEAWLVKHGKAQSQNSLVEKDRRFEIFKDNLRFVDEHNEKNL-SYRLGLTRFADLTNDEY 108

  Fly   366 KERTGLWQRDEAKATGGSAAVVPAYHG-ELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEG 429
            :.:. |..:.|.|....::....|..| |||:..|||:|.||.:||:||.||||||||..|.:||
plant   109 RSKY-LGAKMEKKGERRTSLRYEARVGDELPESIDWRKKGAVAEVKDQGGCGSCWAFSTIGAVEG 172

  Fly   430 LYAVKTGELKEFSEQELLDCDTT-DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQC-HFN 492
            :..:.||:|...|||||:||||: :..|||||||.|::.|...||::.:.:||||.....| ...
plant   173 INQIVTGDLITLSEQELVDCDTSYNEGCNGGLMDYAFEFIIKNGGIDTDKDYPYKGVDGTCDQIR 237

  Fly   493 RTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGGVSHPWKALCSKKNLDH 555
            :....|.:..:.|:|..:|.:::: .:|:.||||.|.|  .|.|.|..|:   :...|..: |||
plant   238 KNAKVVTIDSYEDVPTYSEESLKK-AVAHQPISIAIEAGGRAFQLYDSGI---FDGSCGTQ-LDH 297

  Fly   556 GVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYR----GDNTCGVS 605
            ||:.||||..:..:      ||||:||||..|||.||.|:.|    ....||::
plant   298 GVVAVGYGTENGKD------YWIVRNSWGKSWGESGYLRMARNIASSSGKCGIA 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	18/58 (31%)
		Peptidase_C1A	395..611	CDD:239068	92/219 (42%)
RD21A	NP_564497.1	Inhibitor_I29	50..107	CDD:214853	18/57 (32%)
		Peptidase_C1	137..352	CDD:395062	93/220 (42%)
		GRAN	376..432	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.710