DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and XCP2

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_564126.1	Gene:	XCP2 / 838677	AraportID:	AT1G20850	Length:	356	Species:	Arabidopsis thaliana

Alignment Length:	328	Identity:	135/328 - (41%)
Similarity:	193/328 - (58%)	Gaps:	36/328 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 SHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKY-GITEFADMT 361
            ||  ||:..||..:...|.:.|.:..|:.:|..:|:.|||.|:|  .|:.|.:.: |:.||||::
plant    43 SH--DKLIELFENWISNFEKAYETVEEKFLRFEVFKDNLKHIDE--TNKKGKSYWLGLNEFADLS 103

  Fly   362 SSEYKE-----RTGLWQRDEAKATGGSAAVVPAYHG--ELPKEFDWRQKDAVTQVKNQGSCGSCW 419
            ..|:|:     :|.:.:|||.::....     ||..  .:||..|||:|.||.:|||||||||||
plant   104 HEEFKKMYLGLKTDIVRRDEERSYAEF-----AYRDVEAVPKSVDWRKKGAVAEVKNQGSCGSCW 163

  Fly   420 AFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT-DSACNGGLMDNAYKAIKDIGGLEYEAEYPYK 483
            |||....:||:..:.||.|...|||||:||||| ::.|||||||.|::.|...|||..|.:|||.
plant   164 AFSTVAAVEGINKIVTGNLTTLSEQELIDCDTTYNNGCNGGLMDYAFEYIVKNGGLRKEEDYPYS 228

  Fly   484 AKKNQCHFNRTLSH-VQVAGFVDLPKGNETAMQEWLLANGPISIGINANA--MQFYRGGVSHPWK 545
            .::..|...:..|. |.:.|..|:|..:|.::.: .||:.|:|:.|:|:.  .|||.|||   :.
plant   229 MEEGTCEMQKDESETVTINGHQDVPTNDEKSLLK-ALAHQPLSVAIDASGREFQFYSGGV---FD 289

  Fly   546 ALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG----DNTCGVSE 606
            ..|. .:|||||..||||.|      |...|.||||||||:|||:||.|:.|.    :..||:::
plant   290 GRCG-VDLDHGVAAVGYGSS------KGSDYIIVKNSWGPKWGEKGYIRLKRNTGKPEGLCGINK 347

  Fly   607 MAT 609
            ||:
plant   348 MAS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	18/57 (32%)
		Peptidase_C1A	395..611	CDD:239068	104/223 (47%)
XCP2	NP_564126.1	Inhibitor_I29	51..106	CDD:214853	18/56 (32%)
XCP2	NP_564126.1	Peptidase_C1	138..353	CDD:395062	104/224 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	49	1.000	Domainoid score	I4419
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.710