DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and SAG12

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_568651.1	Gene:	SAG12 / 834629	AraportID:	AT5G45890	Length:	346	Species:	Arabidopsis thaliana

Alignment Length:	349	Identity:	126/349 - (36%)
Similarity:	180/349 - (51%)	Gaps:	49/349 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 NQPVVQARHTRSVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKT 338
            |:.::|.||   :||..|                       .||.|....|...|..:|:.|::.
plant    30 NELIMQKRH---IEWMTK-----------------------HGRVYADVKEENNRYVVFKNNVER 68

  Fly   339 IEELNANEMG-SAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYH-----GELPKE 397
            ||.||:...| :.|..:.:|||:|:.|::.....::...|.::.....:.|..:     |.||..
plant    69 IEHLNSIPAGRTFKLAVNQFADLTNDEFRSMYTGFKGVSALSSQSQTKMSPFRYQNVSSGALPVS 133

  Fly   398 FDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMD 462
            .|||:|.|||.:|||||||.|||||....|||...:|.|:|...|||:|:||||.|..|.|||||
plant   134 VDWRKKGAVTPIKNQGSCGCCWAFSAVAAIEGATQIKKGKLISLSEQQLVDCDTNDFGCEGGLMD 198

  Fly   463 NAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRT-LSHVQVAGFVDLPKGNETAMQEWLLANGPISI 526
            .|::.||..|||..|:.||||.:...|:..:| .....:.|:.|:|..:|.|:.: .:|:.|:|:
plant   199 TAFEHIKATGGLTTESNYPYKGEDATCNSKKTNPKATSITGYEDVPVNDEQALMK-AVAHQPVSV 262

  Fly   527 GINANA--MQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGE 589
            ||....  .|||..||   :...|: ..|||.|..:|||.|  .|..|   |||:|||||.:|||
plant   263 GIEGGGFDFQFYSSGV---FTGECT-TYLDHAVTAIGYGES--TNGSK---YWIIKNSWGTKWGE 318

  Fly   590 QGYYRVYRG----DNTCGVSEMAT 609
            .||.|:.:.    ...||::..|:
plant   319 SGYMRIQKDVKDKQGLCGLAMKAS 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/57 (30%)
		Peptidase_C1A	395..611	CDD:239068	97/222 (44%)
SAG12	NP_568651.1	Inhibitor_I29	38..95	CDD:214853	21/82 (26%)
SAG12	NP_568651.1	Peptidase_C1	130..345	CDD:395062	98/223 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	49	1.000	Domainoid score	I4419
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810