DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and RD21B

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_568620.1	Gene:	RD21B / 834321	AraportID:	AT5G43060	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	327	Identity:	129/327 - (39%)
Similarity:	187/327 - (57%)	Gaps:	41/327 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 KVDHLFYKFQVRFGRRYVST----AERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSS 363
            :|:.::..:.|..|::.::.    ||:..|..||:.||:.|:|.|...: |.|.|:|.|||:|:.
plant    45 EVERIYEAWMVEHGKKKMNQNGLGAEKDQRFEIFKDNLRFIDEHNTKNL-SYKLGLTRFADLTNE 108

  Fly   364 EYKE--------RTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWA 420
            ||:.        :..|...|..:|..|.|         ||...|||::.||..||:|||||||||
plant   109 EYRSMYLGAKPTKRVLKTSDRYQARVGDA---------LPDSVDWRKEGAVADVKDQGSCGSCWA 164

  Fly   421 FSVTGNIEGLYAVKTGELKEFSEQELLDCDTT-DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKA 484
            ||..|.:||:..:.||:|...|||||:||||: :..|||||||.|::.|...||::.||:|||||
plant   165 FSTIGAVEGINKIVTGDLISLSEQELVDCDTSYNQGCNGGLMDYAFEFIIKNGGIDTEADYPYKA 229

  Fly   485 KKNQCHFNR-TLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGGVSHPWKA 546
            ...:|..|| ....|.:..:.|:|:.:|.:::: .||:.|||:.|.|  .|.|.|..||   :..
plant   230 ADGRCDQNRKNAKVVTIDSYEDVPENSEASLKK-ALAHQPISVAIEAGGRAFQLYSSGV---FDG 290

  Fly   547 LCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG----DNTCGVSEM 607
            ||..: |||||:.||||..:..:      ||||:||||.||||.||.::.|.    ...||::..
plant   291 LCGTE-LDHGVVAVGYGTENGKD------YWIVRNSWGNRWGESGYIKMARNIEAPTGKCGIAME 348

  Fly   608 AT 609
            |:
plant   349 AS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	20/60 (33%)
		Peptidase_C1A	395..611	CDD:239068	100/223 (45%)
RD21B	NP_568620.1	Inhibitor_I29	50..109	CDD:214853	20/59 (34%)
		Peptidase_C1	138..353	CDD:278538	101/224 (45%)
		GRAN	377..433	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710