DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and XCP1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_567983.1	Gene:	XCP1 / 829688	AraportID:	AT4G35350	Length:	355	Species:	Arabidopsis thaliana

Alignment Length:	323	Identity:	133/323 - (41%)
Similarity:	189/323 - (58%)	Gaps:	21/323 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 KHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADM 360
            :|....||:..||..:.....:.|.|..|:..|..:||:||..|::.| ||:.|...|:.||||:
plant    39 EHLTNTDKLLELFESWMSEHSKAYKSVEEKVHRFEVFRENLMHIDQRN-NEINSYWLGLNEFADL 102

  Fly   361 TSSEYKER-TGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVT 424
            |..|:|.| .||.:...::....||........:|||..|||:|.||..||:||.||||||||..
plant   103 THEEFKGRYLGLAKPQFSRKRQPSANFRYRDITDLPKSVDWRKKGAVAPVKDQGQCGSCWAFSTV 167

  Fly   425 GNIEGLYAVKTGELKEFSEQELLDCDTT-DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQ 488
            ..:||:..:.||.|...|||||:||||| :|.|||||||.|::.|...|||..|.:|||..::..
plant   168 AAVEGINQITTGNLSSLSEQELIDCDTTFNSGCNGGLMDYAFQYIISTGGLHKEDDYPYLMEEGI 232

  Fly   489 CHFNR-TLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANA--MQFYRGGVSHPWKALCSK 550
            |...: .:..|.::|:.|:|:.::.::.: .||:.|:|:.|.|:.  .|||:|||   :...|.
plant   233 CQEQKEDVERVTISGYEDVPENDDESLVK-ALAHQPVSVAIEASGRDFQFYKGGV---FNGKCG- 292

  Fly   551 KNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG----DNTCGVSEMAT 609
            .:|||||..||||.|      |...|.||||||||||||:|:.|:.|.    :..||:::||:
plant   293 TDLDHGVAAVGYGSS------KGSDYVIVKNSWGPRWGEKGFIRMKRNTGKPEGLCGINKMAS 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	20/56 (36%)
		Peptidase_C1A	395..611	CDD:239068	101/223 (45%)
XCP1	NP_567983.1	Inhibitor_I29	51..106	CDD:214853	20/55 (36%)
XCP1	NP_567983.1	Peptidase_C1	137..352	CDD:395062	102/224 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710