DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and AT4G16190

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_567489.1	Gene:	AT4G16190 / 827311	AraportID:	AT4G16190	Length:	373	Species:	Arabidopsis thaliana

Alignment Length:	322	Identity:	132/322 - (40%)
Similarity:	193/322 - (59%)	Gaps:	25/322 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 DHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEM--GSAKYGITEFADMTSSEYKE 367
            :|.|..|:.::.:.|.:..|...|.|:|:.||:   ....|::  .||.:|:|:|:|:|..|::.
plant    52 EHHFTLFKSKYEKTYATQVEHDHRFRVFKANLR---RARRNQLLDPSAVHGVTQFSDLTPKEFRR 113

  Fly   368 R-TGLWQRDEAKATG-GSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGL 430
            : .||.:|.....|. .:|.::|.  .:||.|||||::.|||.|||||.|||||:||..|.:||.
plant   114 KFLGLKRRGFRLPTDTQTAPILPT--SDLPTEFDWREQGAVTPVKNQGMCGSCWSFSAIGALEGA 176

  Fly   431 YAVKTGELKEFSEQELLDCD---------TTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKK 486
            :.:.|.||...|||:|:|||         :.||.|:||||:||::.....|||..|.:|||..:.
plant   177 HFLATKELVSLSEQQLVDCDHECDPAQANSCDSGCSGGLMNNAFEYALKAGGLMKEEDYPYTGRD 241

  Fly   487 N-QCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALCSK 550
            : .|.|:::.....|:.| .:...:|..:...|:.:||::|.|||..||.|.||||.|:  :|||
plant   242 HTACKFDKSKIVASVSNF-SVVSSDEDQIAANLVQHGPLAIAINAMWMQTYIGGVSCPY--VCSK 303

  Fly   551 KNLDHGVLVVGYGVSDY-PNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DNTCGVSEMATS 610
            .. |||||:||:|.|.| |...|..||||:|||||..|||.|||::.|| .|.||:..|.::
plant   304 SQ-DHGVLLVGFGSSGYAPIRLKEKPYWIIKNSWGAMWGEHGYYKICRGPHNMCGMDTMVST 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/58 (29%)
		Peptidase_C1A	395..611	CDD:239068	106/228 (46%)
AT4G16190	NP_567489.1	Inhibitor_I29	55..110	CDD:214853	17/57 (30%)
AT4G16190	NP_567489.1	Peptidase_C1	140..365	CDD:278538	107/229 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	226	1.000	Domainoid score	I673
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H111629
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2557
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.780