DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and AT3G19390

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_566633.1	Gene:	AT3G19390 / 821473	AraportID:	AT3G19390	Length:	452	Species:	Arabidopsis thaliana

Alignment Length:	343	Identity:	131/343 - (38%)
Similarity:	192/343 - (55%)	Gaps:	44/343 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 SVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGS 349
            ||...|...::..:.|      ::.::.|...:.|....|::.|..||:.|||.:||.::....:
plant    26 SVTATETTRNEAEARR------MYERWLVENRKNYNGLGEKERRFEIFKDNLKFVEEHSSIPNRT 84

  Fly   350 AKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGE---------LPKEFDWRQKDA 405
            .:.|:|.|||:|:.|::   .::.|.:.:.|.     ||. .||         ||...|||.|.|
plant    85 YEVGLTRFADLTNDEFR---AIYLRSKMERTR-----VPV-KGEKYLYKVGDSLPDAIDWRAKGA 140

  Fly   406 VTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT-DSACNGGLMDNAYKAIK 469
            |..||:|||||||||||..|.:||:..:|||||...|||||:||||: :..|.|||||.|:|.|.
plant   141 VNPVKDQGSCGSCWAFSAIGAVEGINQIKTGELISLSEQELVDCDTSYNDGCGGGLMDYAFKFII 205

  Fly   470 DIGGLEYEAEYPYKAKK-NQCHFNRTLSH-VQVAGFVDLPKGNETAMQEWLLANGPISIGINA-- 530
            :.||::.|.:|||.|.. |.|:.::..:. |.:.|:.|:|:.:|.:::: .|||.|||:.|.|
plant   206 ENGGIDTEEDYPYIATDVNVCNSDKKNTRVVTIDGYEDVPQNDEKSLKK-ALANQPISVAIEAGG 269

  Fly   531 NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRV 595
            .|.|.|..||   :...|. .:|||||:.||||.....:      ||||:||||..|||.||:::
plant   270 RAFQLYTSGV---FTGTCG-TSLDHGVVAVGYGSEGGQD------YWIVRNSWGSNWGESGYFKL 324

  Fly   596 YR----GDNTCGVSEMAT 609
            .|    ....|||:.||:
plant   325 ERNIKESSGKCGVAMMAS 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/56 (30%)
		Peptidase_C1A	395..611	CDD:239068	102/224 (46%)
AT3G19390	NP_566633.1	Inhibitor_I29	43..99	CDD:214853	17/55 (31%)
		Peptidase_C1	129..345	CDD:278538	103/225 (46%)
		GRAN	364..420	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710