DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and AT2G21430

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_565512.1	Gene:	AT2G21430 / 816682	AraportID:	AT2G21430	Length:	361	Species:	Arabidopsis thaliana

Alignment Length:	326	Identity:	133/326 - (40%)
Similarity:	192/326 - (58%)	Gaps:	36/326 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 DHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMG-SAKYGITEFADMTSSEYKER 368
            || |..|:.:||:.|.|..|...|..:|:.||  :..:...:|. ||::|:|:|:|:|.||::
plant    46 DH-FTLFKKKFGKVYGSIEEHYYRFSVFKANL--LRAMRHQKMDPSARHGVTQFSDLTRSEFR-- 105

  Fly   369 TGLWQRDEAKATGG--------SAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTG 425
                 |......||        .|.::|..:  ||:|||||.:.|||.|||||||||||:||.||
plant   106 -----RKHLGVKGGFKLPKDANQAPILPTQN--LPEEFDWRDRGAVTPVKNQGSCGSCWSFSTTG 163

  Fly   426 NIEGLYAVKTGELKEFSEQELLDCD---------TTDSACNGGLMDNAYKAIKDIGGLEYEAEYP 481
            .:||.:.:.||:|...|||:|:|||         :.||.||||||::|::.....|||..|.:||
plant   164 ALEGAHFLATGKLVSLSEQQLVDCDHECDPEEEGSCDSGCNGGLMNSAFEYTLKTGGLMREKDYP 228

  Fly   482 YKAKK-NQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWK 545
            |.... ..|..:|:.....|:.| .:...||..:...|:.|||:::.|||..||.|.||||.|:
plant   229 YTGTDGGSCKLDRSKIVASVSNF-SVVSINEDQIAANLIKNGPLAVAINAAYMQTYIGGVSCPY- 291

  Fly   546 ALCSKKNLDHGVLVVGYGVSDYPNFH-KTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMAT 609
             :||:: |:||||:||||.:.:.... |..||||:|||||..|||.|:|::.:|.|.|||..:.:
plant   292 -ICSRR-LNHGVLLVGYGSAGFSQARLKEKPYWIIKNSWGESWGENGFYKICKGRNICGVDSLVS 354

  Fly   610 S 610
            :
plant   355 T 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	20/57 (35%)
		Peptidase_C1A	395..611	CDD:239068	104/227 (46%)
AT2G21430	NP_565512.1	Inhibitor_I29	48..103	CDD:214853	19/56 (34%)
AT2G21430	NP_565512.1	Peptidase_C1	132..356	CDD:395062	105/228 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	226	1.000	Domainoid score	I673
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H111629
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2557
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3186
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.780