DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and si:dkey-228a15.1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_017207744.1	Gene:	si:dkey-228a15.1 / 564472	ZFINID:	ZDB-GENE-060503-344	Length:	313	Species:	Danio rerio

Alignment Length:	202	Identity:	39/202 - (19%)
Similarity:	69/202 - (34%)	Gaps:	52/202 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 NEKYVHR---SRRSANDILGRHKPYDEEAAKAQLQKSLDKLTAGEGPHYKIVKVYSASRQVDSGI 233
            ::|..:|   :|...||.......::.|.....|....||.:         ::....|.|.:..:
Zfish   151 HKKNTYRLWVTRPEGNDAPATPHRFEMEGFNTLLDSHNDKYS---------IEYSDFSSQTEPDV 206

  Fly   234 LT---RIDADLIDGSEEQHRCIVDIWTKVWVRKDEHEITFKCRNQPVVQARHTRSVEWAEKKTHK 295
            .|   ....:......|||:.:.:                     |:.....|..|
Zfish   207 FTPPAGFTCEEFPDPPEQHQILAN---------------------PIQDYVSTNPV--------- 241

  Fly   296 KHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADM 360
            .|:||      :|..|:.:|.|:|.|..|.|.|...|.|:.:.:...|...: |...||.:.||.
Zfish   242 SHAHR------MFGPFKEKFNRQYKSEEEHQEREINFVQSFRFVNSTNRKGL-SFTVGINKRADW 299

  Fly   361 TSSEYKE 367
            :.:|.::
Zfish   300 SRAETRK 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856	10/80 (13%)
		Inhibitor_I29	308..365	CDD:285458	17/56 (30%)
		Peptidase_C1A	395..611	CDD:239068
si:dkey-228a15.1	XP_017207744.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900