Protein Alignment CtsF and Cts8

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_062414.3
• Gene: Cts8 / 56094
• MGIID: 1860275
• Length: 333
• Species: Mus musculus
• Alignment Length: 327
• Identity: 108/327 - (33%)
• Similarity: 158/327 - (48%)
• Gaps: 45/327 - (13%)

  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNAN-EMGSAKY--GITEFADMTSSEY 365
            :|..:.:::.:|.:.|....|.|.| .::.:|:|.:::.|.. :.|...:  .:..|.|||..||
Mouse    25 LDSEWQEWKRKFNKNYSMEEEGQKR-AVWEENMKLVKQHNIEYDQGKKNFTMDVNAFGDMTGEEY 88

  Fly   366 KERTGLWQRDEAKATGGSAAVVPAYH----------GELPKEFDWRQKDAVTQVKNQGSCGSCWA 420
            ::..             :...||.:.          |.|||..|||::..||.|||||:|.||||
Mouse    89 RKML-------------TDIPVPNFRKKKSIHQPIAGYLPKFVDWRKRGCVTPVKNQGTCNSCWA 140

  Fly   421 FSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDS--ACNGGLMDNAYKAIKDIGGLEYEAEYPYK 483
            ||..|.|||....|||:|...|.|.|:||...:.  .|..|....|.|.:....|||.|:.||||
Mouse   141 FSAAGAIEGQMFRKTGKLVPLSTQNLVDCSRLEGNFGCFKGSTFLALKYVWKNRGLEAESTYPYK 205

  Fly   484 AKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQF--YRGGVSHPWKA 546
            .....|.::...|..::..| .....:|..:...:...||||:||:|....|  ||.|:.:..|
Mouse   206 GTDGHCRYHPERSAARITSF-SFVSNSEKDLMRAVATIGPISVGIDARHKSFRLYREGIYYEPK- 268

  Fly   547 LCSKKNLDHGVLVVGYGV----SDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DNTCGVSE 606
             ||...::|.|||||||.    ||...      ||::|||.|.:||..||.::.|| :|.||::.
Mouse   269 -CSSNIINHSVLVVGYGYEGKESDGNK------YWLIKNSHGEQWGMNGYMKLARGRNNHCGIAS 326

  Fly   607 MA 608
            .|
Mouse   327 YA 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	13/59 (22%)
		Peptidase_C1A	395..611	CDD:239068	88/223 (39%)
Cts8	NP_062414.3	Inhibitor_I29	29..87	CDD:214853	13/58 (22%)
		Peptidase_C1A	115..331	CDD:239068	88/223 (39%)