DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12163 and ctss2.1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001019580.2	Gene:	ctss2.1 / 554157	ZFINID:	ZDB-GENE-050522-559	Length:	330	Species:	Danio rerio

Alignment Length:	334	Identity:	112/334 - (33%)
Similarity:	178/334 - (53%)	Gaps:	38/334 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 SHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLK--TIEELNANEMGSAKYGIT--EFA 358
            :|....:|..:..::..:|:.|.:..|...|.:::.:||:  |:..|.|: ||...|.::  ...
Zfish    17 AHFNTNLDQHWELWKKTYGKIYTTEVEEFGRRQLWERNLQLITVHNLEAS-MGMHSYDLSMNHMG 80

  Fly   359 DMTSSEYKERTGL------WQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGS 417
            |:|:.|..:...|      ::|..|...|.|...|       |...|||:|..|:.||.||:|||
Zfish    81 DLTTEEILQTLALTHVPSGFKRQIANIVGSSGDAV-------PDSLDWREKGYVSSVKMQGACGS 138

  Fly   418 CWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEY 480
            |||||..|.:||.....||:|.:.|.|.|:||.:.  :..||||.|.:|::.:.|.||:..::.|
Zfish   139 CWAFSSVGALEGQLKKTTGKLVDLSPQNLVDCSSKYGNKGCNGGFMSDAFQYVIDNGGIASDSAY 203

  Fly   481 PYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQF--YRGGVSHP 543
            ||:..:.||.::.:........:..:.:|:|.|:::.:.:.||||:.|:|...||  |..||.:
Zfish   204 PYRGVQQQCSYSSSQRAANCTKYYFVRQGDENALKQAVASVGPISVAIDATRPQFVLYHSGVYN- 267

  Fly   544 WKALCSKKNLDHGVLVVGYGVSDYPNFHKTL---PYWIVKNSWGPRWGEQGYYRVYRG-DNTCGV 604
             ...|||: ::|.|||||||         ||   .||:||||||.|:|:.||.|:.|. :|.||:
Zfish   268 -DPTCSKR-VNHAVLVVGYG---------TLSGQDYWLVKNSWGTRFGDGGYIRMARNKNNMCGI 321

  Fly   605 SEMATSAVL 613
            :..|...|:
Zfish   322 ASYACYPVM 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	14/60 (23%)
		Peptidase_C1A	395..611	CDD:239068	88/223 (39%)
ctss2.1	NP_001019580.2	PTZ00203	6..324	CDD:185513	110/326 (34%)
		Inhibitor_I29	27..86	CDD:214853	14/59 (24%)
		Peptidase_C1	115..329	CDD:278538	89/232 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.710