Protein Alignment CtsF and Ctss

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_063138486.1
• Gene: Ctss / 50654
• RGDID: 621513
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 335
• Identity: 127/335 - (37%)
• Similarity: 174/335 - (51%)
• Gaps: 58/335 - (17%)

  Fly   288 WAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELN-ANEMGSAK 351
            |  ||||:|.           ||.|          .|..:|..|:.:|||.|...| .:.||...
  Rat    41 W--KKTHEKE-----------YKDQ----------NEEDVRRLIWEKNLKFIMLHNLEHSMGMHS 82

  Fly   352 Y--GITEFADMTSSEYKERTGL------WQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQ 408
            |  |:....|||..|.....|.      |.|        |..:..:.:..||...|||:|..||.
  Rat    83 YSVGMNHMGDMTPEEVIGYMGSLRIPRHWNR--------SGTLKSSSNQTLPDSVDWREKGCVTN 139

  Fly   409 VKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTD----SACNGGLMDNAYKAIK 469
            ||.|||||||||||..|.:||...:|||:|...|.|.|:||.|.:    ..|.||.|..|::.|.
  Rat   140 VKYQGSCGSCWAFSAVGALEGQLKLKTGKLVSLSAQNLVDCSTEEKYGNKGCGGGFMTEAFQYII 204

  Fly   470 DIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQ 534
            |.||::.||.|||||...:||::........:.:::||.|:|.|::|.:...||:|:||:|:...
  Rat   205 DNGGIDSEASYPYKAMDEKCHYDPKNRAATCSRYIELPFGDEEALKEAVATKGPVSVGIDASHSS 269

  Fly   535 F--YRGGV-SHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVY 596
            |  |:.|| ..|   .|: :|::|||||||||..|..:      ||:||||||..:|:|||.|:.
  Rat   270 FFLYQSGVYDDP---SCT-ENVNHGVLVVGYGTLDGKD------YWLVKNSWGLHFGDQGYIRMA 324

  Fly   597 RGD-NTCGVS 605
            |.: |.||::
  Rat   325 RNNKNHCGIA 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	18/59 (31%)
		Peptidase_C1A	395..611	CDD:239068	97/219 (44%)
Ctss	XP_063138486.1	None