DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and RGD1564827

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_017456168.1	Gene:	RGD1564827 / 498689	RGDID:	1564827	Length:	333	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	112/328 - (34%)
Similarity:	167/328 - (50%)	Gaps:	47/328 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGIT----EFADMTSSE 364
            :|..:.|:::::.:.|....|.|.| .::.||:|.| :|:..|.|..|:|.|    .|.|||..|
  Rat    25 LDAEWQKWKIKYEKTYSLEEEGQKR-AVWEQNMKKI-KLHNGENGLGKHGFTMEMNAFGDMTIEE 87

  Fly   365 Y------------KERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGS 417
            :            |:...:.:|...               .:|...:||::..||.|:.||.|.:
  Rat    88 FRKLMIEIPIPTVKKENSVQKRQAV---------------NVPNFINWRKRGYVTPVRRQGRCNA 137

  Fly   418 CWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKA---IKDIGGLEYEAE 479
            ||||||.|.|||....|||:|...|.|.|:||..|.... |..:.|.|.|   :|:.||||.||.
  Rat   138 CWAFSVAGAIEGQMFRKTGQLIPLSVQNLVDCSRTQGNL-GCYLGNTYFALQYVKENGGLESEAT 201

  Fly   480 YPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGGVSH 542
            |||:.|:..|.::...|...:||...:|| ||.|:...:...||||:.|:|  .:..|||.|:.|
  Rat   202 YPYEGKEGSCRYHPDNSTASIAGIEFVPK-NEHALMNAVATLGPISVAIDARHESFLFYRNGIYH 265

  Fly   543 PWKALCSKKNLDHGVLVVGYG-VSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGD-NTCGVS 605
              :..|:...:.|.:|:|||| |.:..:..|   |||||||.|.:||.:||.::.:.. |.||::
  Rat   266 --EPNCNSSVVTHSMLLVGYGFVGEESDGRK---YWIVKNSMGNKWGNRGYMKIAKDQGNHCGIA 325

  Fly   606 EMA 608
            ..|
  Rat   326 TYA 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	19/60 (32%)
		Peptidase_C1A	395..611	CDD:239068	89/221 (40%)
RGD1564827	XP_017456168.1	PTZ00203	2..327	CDD:185513	111/325 (34%)
		Inhibitor_I29	29..87	CDD:214853	19/59 (32%)
		Peptidase_C1A	115..331	CDD:239068	89/221 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810