Protein Alignment CtsF and ctsh

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_031753756.1
• Gene: ctsh / 496748
• XenbaseID: XB-GENE-5820392
• Length: 330
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 101/339 - (29%)
• Similarity: 160/339 - (47%)
• Gaps: 60/339 - (17%)

  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELN-ANEMGSAKY--GITEFADMTSSEY 365
            :|..:..::.::.::|.|:.:...|.:.:..|...:.:.| ..:.|..||  .:..||||||.|.
 Frog    21 LDEEWNTWKEKYEKKYASSEDELFRRKAWEVNWDKVTKHNQLADQGLKKYTMAMNHFADMTSEEM 85

  Fly   366 KERTGLWQRDEAKATGGSAAVVPAY--------------HGELPKEFDWRQKDAVTQVKNQGSCG 416
            ..|.               ..:|.:              |.::.|..|||..:.::.|||||.||
 Frog    86 NSRN---------------CFLPTHYPSKHKPAPRYNVKHAKISKGVDWRDSNCISPVKNQGYCG 135

  Fly   417 SCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYP 481
            |||||:..|.:|.|:.:...||...|||:|:|||..|..|.||...||...|...|.::.| :|.
 Frog   136 SCWAFATVGVLEALHCLNGNELHNLSEQQLVDCDPIDHGCCGGFPINAIDYITQEGIMKSE-DYE 199

  Fly   482 YKAKKNQCHFNRTLS-HVQVAGFVDLPKGNETAMQEWLLANGPISIGINANA-MQFYRGGVSHPW 544
            |:.|:..|.::.:.: .:.|:.:..||  ||..|...:..:|||::|...|. ...|..|:   :
 Frog   200 YEEKQFYCRYDSSNAIQLNVSKYYVLP--NEENMASSVAKDGPITVGFGVNRDFMLYSKGI---F 259

  Fly   545 KALCSKKNLDHGVLVVGYGVSDYPNFHKTL----------PYWIVKNSWGPRWGEQGYYRVYRGD 599
            ...|:.:. :|.:::||||         ||          .|||:|||||..|||.|:.::.|..
 Frog   260 DGECAPRP-NHAIIIVGYG---------TLHCEEGKDDGEDYWIIKNSWGTEWGEDGFGKIMRNK 314

  Fly   600 NTCGVSEMATSAVL 613
            :.||:||.|.|..|
 Frog   315 DMCGISEFAASLEL 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	14/59 (24%)
		Peptidase_C1A	395..611	CDD:239068	80/227 (35%)
ctsh	XP_031753756.1	Inhibitor_I29	25..84	CDD:214853	14/58 (24%)
		Peptidase_C1A	117..324	CDD:239068	78/222 (35%)