DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and ctss

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001005695.1	Gene:	ctss / 448203	XenbaseID:	XB-GENE-953011	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	346	Identity:	122/346 - (35%)
Similarity:	180/346 - (52%)	Gaps:	51/346 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 VVQARHTRSVE-----WAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNL 336
            :|:||...:::     |  |.||.|...  |:::.|                  |.|: .:.:||
Frog    14 IVKARINPALDNHWLLW--KNTHNKDYE--DEIEDL------------------QRRI-TWEKNL 55

  Fly   337 KTIEELNAN-EMGSAKY--GITEFADMTSSEYKER-TGLW--QRDEAKATGGSAAVVPAYHGELP 395
            ..:...|.. .||...|  |:...|||||.|.|.: |||.  .:.|.:|| .|:.....:.|::|
Frog    56 NLVNMHNLEYSMGMHTYELGMNHLADMTSEEIKSKLTGLILPPQSERQAT-FSSQKNSTFGGKVP 119

  Fly   396 KEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNG 458
            ...|||.|..|:.|||||.||||||||..|.:||...:|||:|...|.|.|:||.:.  :..|.|
Frog   120 DSIDWRDKGCVSDVKNQGGCGSCWAFSAVGALEGQLMLKTGKLVSLSPQNLVDCSSKYGNKGCGG 184

  Fly   459 GLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGP 523
            |.|..|::.:.|..|::.::.|||.|...:||::.|......|.:.::..|.|..:::.|.:.||
Frog   185 GFMTQAFQYVIDNKGIDSDSYYPYHAMDEKCHYDPTGKASTCAKYTEIVPGTEDNLKQALGSIGP 249

  Fly   524 ISIGINANAMQF--YRGGV-SHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGP 585
            ||:.|:.....|  ||.|| |.|   .||.: ::||||.||||..:..:|      |::|||||.
Frog   250 ISVAIDGTRPSFFLYRSGVYSDP---TCSHE-VNHGVLAVGYGNLNGQDF------WLLKNSWGT 304

  Fly   586 RWGEQGYYRVYRG-DNTCGVS 605
            ::|:|||.|:.|. .|.|||:
Frog   305 KYGDQGYVRIARNKGNLCGVA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	14/59 (24%)
		Peptidase_C1A	395..611	CDD:239068	88/217 (41%)
ctss	NP_001005695.1	Inhibitor_I29	27..87	CDD:369782	21/82 (26%)
ctss	NP_001005695.1	Peptidase_C1A	119..331	CDD:239068	88/217 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910