DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Y71H2AM.25

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001040887.1	Gene:	Y71H2AM.25 / 4363054	WormBaseID:	WBGene00044760	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	95/321 - (29%)
Similarity:	150/321 - (46%)	Gaps:	62/321 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 RYVSTAERQMRLRI--------FRQNLKTIEELNANEMGSAK----YGITEFADMTSSEYKERTG 370
            |.:|.|:...:.::        |.:..|:..:||:..:.:..    |.|.......:||....|.
Worm     6 RLISKADEAKKQKVFVALGEDFFEKPAKSRNKLNSIILFTLTALTFYIIGYLVQQRTSESLPTTF 70

  Fly   371 LWQRDEAKATGGSAAVVPAYHGELPKEF-DWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVK 434
            .|:             .|.|..:..:|| |||.|..|..||:||.|.:..||:::.:||.:||..
Worm    71 QWK-------------TPKYTIQTTEEFLDWRDKGIVGPVKDQGKCNASHAFAISSSIESMYAKA 122

  Fly   435 T-GELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKD-----------IGGLEYEAEYPYKAKKN 487
            | |.|..||||:|:|||           |:.:|..::           ..|:|.||:|||..|:|
Worm   123 TNGSLLSFSEQQLIDCD-----------DHGFKGCEEQPAINAVSYFIFHGIETEADYPYAGKEN 176

  Fly   488 -QCHFNRTLSHVQV--AGFVDLPKGNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALC 548
             :|.|:.|.|.:|:  |.||   ..|||..:|.:...||....:.| .::..|:.|:.:|....|
Worm   177 GKCTFDSTKSKIQLKDAEFV---VSNETQGKELVTNYGPAFFTMRAPPSLYDYKIGIYNPSIEEC 238

  Fly   549 SKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMAT 609
            :..:....:::||||:.....      |||||.|:|..||||||.::.|..|.|.:::..|
Worm   239 TSTHEIRSMVIVGYGIEGVQK------YWIVKGSFGTSWGEQGYMKLARDVNACAMADFIT 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	10/58 (17%)
		Peptidase_C1A	395..611	CDD:239068	80/232 (34%)
Y71H2AM.25	NP_001040887.1	Peptidase_C1A	84..295	CDD:239068	80/230 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820