DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and CG11459

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001287191.1	Gene:	CG11459 / 40741	FlyBaseID:	FBgn0037396	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	333	Identity:	95/333 - (28%)
Similarity:	155/333 - (46%)	Gaps:	32/333 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 RFDKVDHLFYKFQVRFGRRYVSTAE---------RQMRLR------IFRQNLKTIE---ELNANE 346
            |...|..|.....|..|...||..|         :|.|.|      ::.|.:..:|   :|....
  Fly     5 RLTVVHGLILLLLVELGLTAVSDTEWDQYKAKYNKQYRNRDKYHRALYEQRVLAVESHNQLYLQG 69

  Fly   347 MGSAKYGITEFADMTSSE--YKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQV 409
            ..:.|.|:.:|:| |...  :..|:.:....|......:..|....:.::.:..||||...::.|
  Fly    70 KVAFKMGLNKFSD-TDQRILFNYRSSIPAPLETSTNALTETVNYKRYDQITEGIDWRQYGYISPV 133

  Fly   410 KNQGS-CGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDC-DTTDSACNGGLMDNAYKAIKDIG 472
            .:||: |.||||||.:|.:|...|.|.|.|...|.:.|:|| ...::.|:||.:..|:...:| .
  Fly   134 GDQGTECLSCWAFSTSGVLEAHMAKKYGNLVPLSPKHLVDCVPYPNNGCSGGWVSVAFNYTRD-H 197

  Fly   473 GLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQF-- 535
            |:..:..|||:....:|.:....|...::|:|.|...:|..:.|.:...||:::.|:....:|
  Fly   198 GIATKESYPYEPVSGECLWKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSIDHLHEEFDQ 262

  Fly   536 YRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYR-GD 599
            |.|||.........:::|.|.||:||:|     ...|...|||:|||:|..|||.||.::.| .:
  Fly   263 YSGGVLSIPACRSKRQDLTHSVLLVGFG-----THRKWGDYWIIKNSYGTDWGESGYLKLARNAN 322

  Fly   600 NTCGVSEM 607
            |.|||:.:
  Fly   323 NMCGVASL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	16/76 (21%)
		Peptidase_C1A	395..611	CDD:239068	73/218 (33%)
CG11459	NP_001287191.1	Inhibitor_I29	30..85	CDD:285458	11/55 (20%)
CG11459	NP_001287191.1	Peptidase_C1A	120..334	CDD:239068	73/217 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452960
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740