Protein Alignment CtsF and ctsba

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_998501.1
• Gene: ctsba / 406645
• ZFINID: ZDB-GENE-040426-2650
• Length: 330
• Species: Danio rerio
• Alignment Length: 301
• Identity: 78/301 - (25%)
• Similarity: 125/301 - (41%)
• Gaps: 63/301 - (20%)

  Fly   357 FADMTSSEYKERTGLWQRDEAKATGGSAAVVPAY-HG-ELPKEFD----WRQKDAVTQVKNQGSC 415
            |.|:..|..|:..|.:.:      |....|:..| .| :|||.||    |.....:.::::||||
Zfish    46 FRDVDYSYVKKLCGTFLK------GPKLPVMVQYTEGLKLPKNFDAREQWPNCPTLKEIRDQGSC 104

  Fly   416 GSCWAFSVTGNIEGLYAVKTGELK---EFSEQELLD-CDTTDSACNGGLMDNAYK--AIKDI--G 472
            ||||||.....|.....:.: :.|   |.|.|:||. ||:....||||....|:.  |.:.:  |
Zfish   105 GSCWAFGAAEAISDRVCIHS-DAKVSVEISSQDLLTCCDSCGMGCNGGYPSAAWDFWATEGLVTG 168

  Fly   473 GLEYEAEY---PYKAKKNQCHFNRTL-----------------------SHVQVAGF----VDLP 507
            || |.:..   ||..:..:.|.|.:.                       |:.|...|    ..:|
Zfish   169 GL-YNSHIGCRPYTIEPCEHHVNGSRPPCSGEGGDTPNCDMKCEPGYSPSYKQDKHFGKTSYSVP 232

  Fly   508 KGNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFH 571
            ....:.|.| |..|||:...... .....|:.||   ::.:.......|.:.::|:|..:
Zfish   233 SNQNSIMAE-LFKNGPVEGAFTVYEDFLLYKSGV---YQHMSGSPVGGHAIKILGWGEEN----- 288

  Fly   572 KTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAV 612
             .:|||:..|||...||:.||:::.||::.||:.....:.:
Zfish   289 -GVPYWLAANSWNTDWGDNGYFKILRGEDHCGIESEIVAGI 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	3/7 (43%)
		Peptidase_C1A	395..611	CDD:239068	68/258 (26%)
ctsba	NP_998501.1	Propeptide_C1	25..64	CDD:462365	5/23 (22%)
		Peptidase_C1A_CathepsinB	80..327	CDD:239111	68/258 (26%)