DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and 26-29-p

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_620470.1	Gene:	26-29-p / 39547	FlyBaseID:	FBgn0250848	Length:	549	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	140/456 - (30%)
Similarity:	205/456 - (44%)	Gaps:	55/456 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 ILGRHKPYDEEAAKAQLQKSLDKL----TAGE-------------GPHYKI----VKVYSASRQV 229
            ||...||:.....::.|..:.||.    |.|:             .|||..    :.|....|..
  Fly   113 ILPDAKPFSLVGTESFLGYTCDKFRLESTIGQKKNIYTLWVRYKKSPHYPSSRMPIPVRYEMRGY 177

  Fly   230 DSGILTRIDADLIDGSEEQHRCIVDIWTKVWVRKDEHEITFKCRNQPVVQARHTRSVEWAEKKTH 294
            ::.:.:..|...:|....:|.   ||..:|:    |.:.:.:|...|.....|..:....::...
  Fly   178 NTLLGSHYDHYYLDYDSYEHD---DIPNEVF----EIDDSLQCVGFPGPGTGHYATFNPMQEFIS 235

  Fly   295 KKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFAD 359
            ....|    ||..|:.|:.:.|..|.|..|.:.|..||||||:.|...|..:: :....:...||
  Fly   236 GTDEH----VDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNRAKL-TYTLAVNHLAD 295

  Fly   360 MTSSEYKERTGLWQRDEAKATGGSAAV-VPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSV 423
            .|..|.|.|.| ::......||..... ||.|..|:|.::|||...|||.||:|..|||||:|..
  Fly   296 KTEEELKARRG-YKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359

  Fly   424 TGNIEGLYAVKT-GELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEY-PYKA 484
            .|::||.:.:|. |.|...|:|.|:||...  ::.|:||.....|:.:...||:..|.|| ||..
  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLG 424

  Fly   485 KKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGVSHPWKAL 547
            :...||.|.......:.|||::...:..|.:..||.:||:|:.|:|:  ...||..||.  ::..
  Fly   425 QDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVY--YEPT 487

  Fly   548 CSKKN----LDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMA 608
            |  ||    |||.||.||||..:..:      ||:|||||...||..||..:....|.|||..|.
  Fly   488 C--KNDVDGLDHAVLAVGYGSINGED------YWLVKNSWSTYWGNDGYILMSAKKNNCGVMTMP 544

  Fly   609 T 609
            |
  Fly   545 T 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856	17/98 (17%)
		Inhibitor_I29	308..365	CDD:285458	18/56 (32%)
		Peptidase_C1A	395..611	CDD:239068	85/225 (38%)
26-29-p	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	18/55 (33%)
26-29-p	NP_620470.1	Peptidase_C1A	331..547	CDD:239068	85/225 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4265
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.690