DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Swim

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_611652.2	Gene:	Swim / 37537	FlyBaseID:	FBgn0034709	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	233	Identity:	71/233 - (30%)
Similarity:	102/233 - (43%)	Gaps:	26/233 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 LPKEFDWRQK--DAVTQVKNQGSCGSCWAFSVTGNIEGLYAV--KTGELKEFSEQELLDCDTTDS 454
            ||..|:...|  ..:::|.:||.||:.|..|.|......:|:  |..|..:.|.|.:|.|.....
  Fly   187 LPSSFNALDKWSSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQQ 251

  Fly   455 ACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQC---HFNRTL--SHVQVAGFVDLPK------ 508
            .|.||.:|.|::.:...|.:: |..|||...::.|   |.:|:|  :..|....||...
  Fly   252 GCEGGHLDAAWRYLHKKGVVD-ENCYPYTQHRDTCKIRHNSRSLRANGCQKPVNVDRDSLYTVGP 315

  Fly   509 ----GNETAMQEWLLANGPISIGINANAMQF-YRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYP 568
                ..|..:...:..:||:...:..|...| |.|||.....|........|.|.:||:|..
  Fly   316 AYSLNREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEE--- 377

  Fly   569 NFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSE 606
              |....|||..||||..|||.||:|:.||.|.||:.|
  Fly   378 --HNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEE 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458
		Peptidase_C1A	395..611	CDD:239068	70/232 (30%)
Swim	NP_611652.2	Somatomedin_B	41..83	CDD:279385
		VWC	91..>126	CDD:302663
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	70/232 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840