DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and CG4847

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	113/317 - (35%)
Similarity:	168/317 - (52%)	Gaps:	19/317 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 FYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELN---ANEMGSAKYGITEFADMTSSEY-KER 368
            |..|..:.|:.|:|.|:|.:....|......:|..|   |..:.:.|..:..|||:|.||: .:.
  Fly   112 FGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQL 176

  Fly   369 TGLWQRDEAKA-TGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYA 432
            |||.:..|||| ...|..:|......:|..||||:...||.||.||:|||||||:.||.|||...
  Fly   177 TGLKRSPEAKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTF 241

  Fly   433 VKTGELKEFSEQELLDCDTTD----SACNGGLMDNAYKAIKDI-GGLEYEAEYPYKAKKNQCHFN 492
            .|||.|...|||.|:||...:    :.|:||..:.|:..|.:: .|:..|..|||...|..|.::
  Fly   242 RKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYD 306

  Fly   493 RTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALCSKKNLDHG 556
            .:.|...:.||..:|..:|..:::.:...||::..:|. ..::.|.||:.:..:  |:|...:|.
  Fly   307 GSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIYNDDE--CNKGEPNHS 369

  Fly   557 VLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            :||||||      ..|...||||||||...|||:||:|:.||.|.|.::|..:..|:
  Fly   370 ILVVGYG------SEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEECSYPVV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/59 (29%)
		Peptidase_C1A	395..611	CDD:239068	85/221 (38%)
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	17/59 (29%)
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	85/221 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740