DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and CG6357

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_610907.1	Gene:	CG6357 / 36532	FlyBaseID:	FBgn0033875	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	62/299 - (20%)
Similarity:	107/299 - (35%)	Gaps:	92/299 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 EEAAKAQLQKSLDKLTAGEGPHYKIVKVYSASRQVDSGILTRIDADLIDGSEEQHRCIVD--IWT 257
            ||..|...|.:.:|.....|..||........|.|...               ..|.||:  :..
  Fly   151 EERDKVNCQAAWEKFLIDFGAQYKNANETEKRRNVFCA---------------NWRAIVEHNVQY 200

  Fly   258 KVWVRKDEHEI------TFKCRNQPVVQARHTRSVEWAEKKTHKKHSHRFDKVDH-------LFY 309
            :.|....:.:|      |.:.|:.|..:.|.    |.|...|        .::|:       .:.
  Fly   201 EKWAEPFKRDINQWTDHTIEERSSPAPEIRK----EEATTST--------SEIDNDNIICQPAWE 253

  Fly   310 KFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNAN-EMG--SAKYGITEFADMTSSEYKERTGL 371
            ||.:.|...|....|.:.|..:|..|.|:|.:.|.. ::|  |.|.||.:::|:|..|:|.:
  Fly   254 KFLIDFKPSYQDDTETEKRRNVFCDNFKSIHKHNVQFDLGNISFKKGINQWSDLTVEEWKNK--- 315

  Fly   372 WQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQV----KNQGSCGSCW-AFSVTGNIEGLY 431
             ||             ||::.|..|      .:|.|::    ::..:|.:.| .|.:.      :
  Fly   316 -QR-------------PAFNPEFSK------VEATTKISKDKRDDNTCQAAWKKFLID------F 354

  Fly   432 AVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKD 470
            ..|..:.||..::..:.||.             :|||::
  Fly   355 GAKYQDEKETEKRRTIFCDN-------------WKAIQE 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856	16/84 (19%)
		Inhibitor_I29	308..365	CDD:285458	18/59 (31%)
		Peptidase_C1A	395..611	CDD:239068	14/81 (17%)
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458
		Inhibitor_I29	162..221	CDD:214853	12/73 (16%)
		Inhibitor_I29	252..311	CDD:214853	18/58 (31%)
		Inhibitor_I29	347..406	CDD:214853	10/53 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900