DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and CG6347

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	108/335 - (32%)
Similarity:	163/335 - (48%)	Gaps:	49/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 FYKFQVRFGRRYVSTAERQMRLRIF--RQNLKTIEELNA-NEMGSAKYGITEFADMTS------- 362
            |..|..:.|:.| |..||..|..||  :.:|.|:...|| |.:...:.|:...||||.
  Fly    38 FDDFLRQTGKVY-SDEERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLL 101

  Fly   363 ----SEYKERTGLWQRDEAKATGGSAAVVPAYH---GELPKEFDWRQKDAVTQVKNQG-SCGSCW 419
                ||:.||          .|.|....|.|.:   ..||:.||||:|..||....|| .||:||
  Fly   102 GSKISEFGER----------YTNGHINFVTARNPASANLPEMFDWREKGGVTPPGFQGVGCGACW 156

  Fly   420 AFSVTGNIEGLYAVKTGELKEFSEQELLDC--DTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPY 482
            :|:.||.:||....:||.|...|:|.|:||  |..:..|:||..:..::.|:| .|:....:|||
  Fly   157 SFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQEYGFEYIRD-HGVTLANKYPY 220

  Fly   483 KAKKNQCHFNRTL------SHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQF--YRGG 539
            ...:.||..|.|.      |.|::..:..:..|:|..|:|.:...||::..:||:.:.|  |.||
  Fly   221 TQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGG 285

  Fly   540 VSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYR-GDNTCG 603
            :....:  |::..|:|.|.|||||..:..:      |||:|||:...|||.|:.|:.| ....||
  Fly   286 IYEDEE--CNQGELNHSVTVVGYGTENGRD------YWIIKNSYSQNWGEGGFMRILRNAGGFCG 342

  Fly   604 VSEMATSAVL 613
            ::...:..:|
  Fly   343 IASECSYPIL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	21/70 (30%)
		Peptidase_C1A	395..611	CDD:239068	78/227 (34%)
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	20/59 (34%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	78/227 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740