DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and CG5367

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	106/316 - (33%)
Similarity:	167/316 - (52%)	Gaps:	23/316 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 FYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNAN-EMGSAKYGITE--FADMTSSEY-KER 368
            |.||:....|:|:.|.:.....:.|.:|.|.|||.|.| :.|...:.:..  ||||::..| |..
  Fly    36 FEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGF 100

  Fly   369 TGLWQRDEAKATGGSAAVVPA-YHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYA 432
            ..|.:.:...:....|.:|.: ....:|:..|||.|..:|...||.|||||:|||:..:|.|...
  Fly   101 LRLLKSNIEDSADNMAEIVGSPLMANVPESLDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVF 165

  Fly   433 VKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTL 495
            .:||::...|:|:::||..:  :..|.||.:.|....::..||:..:.:|||.|:|.:|.|...|
  Fly   166 KRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKGKCQFVPDL 230

  Fly   496 SHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGV-SHPWKALCSKKNLDHGV 557
            |.|.|..:..||..:|.|:|..:...||::|.|||:  ..|.|..|: ..|   |||..:::|.:
  Fly   231 SVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDP---LCSSASVNHAM 292

  Fly   558 LVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            :|:|:|..          |||:||.||..|||.||.|:.:|.|.||::..|..|::
  Fly   293 VVIGFGKD----------YWILKNWWGQNWGENGYIRIRKGVNMCGIANYAAYAIV 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	19/59 (32%)
		Peptidase_C1A	395..611	CDD:239068	81/220 (37%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	19/59 (32%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	81/220 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452958
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840