DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and si:dkey-239j18.2

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001274132.1	Gene:	si:dkey-239j18.2 / 321853	ZFINID:	ZDB-GENE-121214-52	Length:	335	Species:	Danio rerio

Alignment Length:	318	Identity:	120/318 - (37%)
Similarity:	190/318 - (59%)	Gaps:	20/318 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 KVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNAN-EMG--SAKYGITEFADMTSSE 364
            ::|..:..::.:.|:.|....|...|: |:.:||:.||:.|.. .:|  :.|.|:.:|.|||:.|
Zfish    23 QLDDHWNSWKSQHGKSYHEDVEVGRRM-IWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEE 86

  Fly   365 YKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEG 429
            :::....::.|..:.:.|...:.|.:.. .|::.||||:..||.||:|..|||||:||.||.:||
Zfish    87 FRQAMNGYKHDPNRTSQGPLFMEPKFFA-APQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEG 150

  Fly   430 LYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKN-QCHF 491
            ....|||:|...|||.|:||...  :..|||||||.|::.:|:..||:.|..|||.|:.: .|.:
Zfish   151 QLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRY 215

  Fly   492 NRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGVSHPWKALCSKKNLD 554
            :...:..::.||||:|||||.|:...:.|.||:|:.|:|:  ::|||:.|:.  ::..|:.: ||
Zfish   216 DPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIY--YERACTSQ-LD 277

  Fly   555 HGVLVVGYGV--SDYPNFHKTLPYWIVKNSWGPRWGEQGY-YRVYRGDNTCGVSEMAT 609
            |.|||||||.  :|.....    ||||||||..:||::|| |.....:|.||::.||:
Zfish   278 HAVLVVGYGYQGADVAGNR----YWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMAS 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/59 (29%)
		Peptidase_C1A	395..611	CDD:239068	98/223 (44%)
si:dkey-239j18.2	NP_001274132.1	Inhibitor_I29	28..86	CDD:214853	17/58 (29%)
si:dkey-239j18.2	NP_001274132.1	Peptidase_C1	115..334	CDD:278538	98/224 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810