DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12163 and Ctsm

DIOPT Version :9

Sequence 1:NP_730901.1 Gene:CG12163 / 40628 FlyBaseID:FBgn0260462 Length:614 Species:Drosophila melanogaster
Sequence 2:NP_852043.2 Gene:Ctsm / 306720 RGDID:631420 Length:333 Species:Rattus norvegicus


Alignment Length:331 Identity:111/331 - (33%)
Similarity:166/331 - (50%) Gaps:53/331 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGIT----EFADMTSSE 364
            :|..:.|:::::.:.|....|.|.| .::.:|:|.| :|:..|.|..|:|.|    .|.|||..|
  Rat    25 LDAEWQKWKIKYEKTYSLEEEGQKR-AVWEENMKKI-KLHNGENGLGKHGFTMEMNAFGDMTIEE 87

  Fly   365 Y------------KERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGS 417
            :            |:...:.:|...               .:|...:||::..||.|:.||.|..
  Rat    88 FRKLMIEIPIPTVKKENSVQKRQAV---------------NVPNFINWRKRGYVTPVRRQGRCNV 137

  Fly   418 CWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGL---MDNAYKA---IKDIGGLEY 476
            ||||||.|.|||....|||:|...|.|.|:||    |...|.|   :.|.|.|   :|:.||||.
  Rat   138 CWAFSVAGAIEGQMFQKTGQLIPLSVQNLVDC----SRPQGNLGCYLGNTYLALQYVKENGGLES 198

  Fly   477 EAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGG 539
            ||.|||:.|:..|.::...|...:..|..:|| ||.|:...:...||||:.|:|  .:..|||.|
  Rat   199 EATYPYEEKEGSCRYHPDNSTASITDFEFVPK-NEDALMNAVATLGPISVAIDARHESFLFYRNG 262

  Fly   540 VSHPWKALCSKKNLDHGVLVVGYG-VSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGD-NTC 602
            :.|  :..||...:.|.:|:|||| |.:..:..|   |||:|||.|.:||.:||.::.:.. |.|
  Rat   263 IYH--EPNCSSSVVTHAMLLVGYGFVGEESDGRK---YWILKNSMGNKWGNRGYMKIAKDQGNHC 322

  Fly   603 GVSEMA 608
            |::..|
  Rat   323 GIATYA 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12163NP_730901.1 CY 194..272 CDD:298856
Inhibitor_I29 308..365 CDD:285458 18/60 (30%)
Peptidase_C1A 395..611 CDD:239068 89/224 (40%)
CtsmNP_852043.2 Inhibitor_I29 29..87 CDD:214853 18/59 (31%)
Peptidase_C1A 115..331 CDD:239068 89/224 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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