DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and RGD1564657

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_038952317.1	Gene:	RGD1564657 / 306718	RGDID:	1564657	Length:	331	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	112/308 - (36%)
Similarity:	171/308 - (55%)	Gaps:	18/308 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 RFGRRYVSTAERQMRLRIFRQNLKTIEE---LNANEMGSAKYGITEFADMTSSEYKERTGLWQRD 375
            |...:..|..|.:.|..::.:|:|.|::   .|...|.:....:.:|.|||..|.:     ...|
  Rat    34 RSNEKTYSPEEEEQRRALWEENVKMIKQHTVENGLWMNNFTIEMNQFCDMTDEEMR-----MMID 93

  Fly   376 EAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKE 440
            .:..|......|...:.|:||..|||:...||.|:.||:||:||.|:|.|:|||....|||:|..
  Rat    94 SSAPTLRKEKRVQKRNVEIPKTLDWRKDGYVTPVRRQGACGACWGFAVAGSIEGQLFKKTGKLSP 158

  Fly   441 FSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGF 503
            .|.|.|:||..:  ...||||.:.||::.:|:.||||.||.|||:||:..|.:....|.|:|..|
  Rat   159 LSVQNLVDCSRSFGTMGCNGGRIYNAFQYVKNNGGLEAEATYPYEAKEGNCRYRPEKSVVKVTRF 223

  Fly   504 VDLPKGNETAMQEWLLANGPISIGINANAMQF--YRGGVSHPWKALCSKKNLDHGVLVVGYGVSD 566
            :.:|: ||.|:...|:..|||::||:|....|  |.||:.|  :..|.:.:.:|.:|:||:|...
  Rat   224 LVVPR-NEEALINALVNIGPIAVGIDAQHESFKKYAGGIYH--EPNCKRDSPNHSMLLVGFGYEG 285

  Fly   567 YPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNT-CGVSEMATSAVL 613
            ..:  :...||:||||:|.:|||:||.::.||.|. ||::..|...||
  Rat   286 QES--EGRKYWLVKNSYGEQWGEKGYMKIPRGQNNYCGIASYAMYPVL 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	13/53 (25%)
		Peptidase_C1A	395..611	CDD:239068	92/220 (42%)
RGD1564657	XP_038952317.1	Inhibitor_I29	29..87	CDD:214853	13/52 (25%)
RGD1564657	XP_038952317.1	Peptidase_C1A	113..329	CDD:239068	92/220 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810