DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Testin

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_775155.1	Gene:	Testin / 286916	RGDID:	708447	Length:	333	Species:	Rattus norvegicus

Alignment Length:	344	Identity:	124/344 - (36%)
Similarity:	178/344 - (51%)	Gaps:	53/344 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 VEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSA 350
            |||.|.:|  ||                  |:.|....|| ::..::.:|.|.| ||:..|....
  Rat    27 VEWNEWRT--KH------------------GKTYNMNEER-LKRAVWEKNFKMI-ELHNWEYLEG 69

  Fly   351 KYGIT----EFADMTSSEY-KERTGLWQRDEAKATGGSAAVVPAYHGEL--PKEFDWRQKDAVTQ 408
            ::..|    .|.|:|:.|: |..|| :||.:.|.|.     :...|..|  ||..||||...||.
  Rat    70 RHDFTMAMNAFGDLTNIEFVKMMTG-FQRQKIKKTH-----IFQDHQFLYVPKRVDWRQLGYVTP 128

  Fly   409 VKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDC--DTTDSACNGGLMDNAYKAIKDI 471
            |||||.|.|.||||.||::||....||..|...|||.||||  ......|:||.|..|::.:||.
  Rat   129 VKNQGHCASSWAFSATGSLEGQMFRKTERLIPLSEQNLLDCMGSNVTHGCSGGFMQYAFQYVKDN 193

  Fly   472 GGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQ 534
            |||..|..|||:.:..:|.::...|...|..||.:| |:|.|:.:.:...||||:.::|:  :.|
  Rat   194 GGLATEESYPYRGQGRECRYHAENSAANVRDFVQIP-GSEEALMKAVAKVGPISVAVDASHGSFQ 257

  Fly   535 FYRGGVSHPWKALCSKKNLDHGVLVVGYGV----SDYPNFHKTLPYWIVKNSWGPRWGEQGYYRV 595
            ||..|:.  ::..|.:.:|:|.|||||||.    ||..:|      |:||||||..||.:||.::
  Rat   258 FYGSGIY--YEPQCKRVHLNHAVLVVGYGFEGEESDGNSF------WLVKNSWGEEWGMKGYMKL 314

  Fly   596 YRG-DNTCGVSEMATSAVL 613
            .:. .|.||::..:|..::
  Rat   315 AKDWSNHCGIATYSTYPIV 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	14/60 (23%)
		Peptidase_C1A	395..611	CDD:239068	93/224 (42%)
Testin	NP_775155.1	Inhibitor_I29	29..87	CDD:214853	19/79 (24%)
Testin	NP_775155.1	Peptidase_C1	114..332	CDD:395062	93/226 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810