Protein Alignment CtsF and Ctsl

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_037288.1
• Gene: Ctsl / 25697
• RGDID: 2448
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 128/342 - (37%)
• Similarity: 189/342 - (55%)
• Gaps: 43/342 - (12%)

  Fly   283 TRSVEWAE-KKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANE 346
            |.:.:|.: |.||                      ||...|.|.:.|..::.:|::.| :|:..|
  Rat    24 TFNAQWHQWKSTH----------------------RRLYGTNEEEWRRAVWEKNMRMI-QLHNGE 65

  Fly   347 MGSAKYGIT----EFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVT 407
            ..:.|:|.|    .|.|||:.|:::....::..:.|.  |.....|... ::||..|||:|..||
  Rat    66 YSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHKK--GRLFQEPLML-QIPKTVDWREKGCVT 127

  Fly   408 QVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDC--DTTDSACNGGLMDNAYKAIKD 470
            .|||||.||||||||.:|.:||...:|||:|...|||.|:||  |..:..|||||||.|::.||:
  Rat   128 PVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKE 192

  Fly   471 IGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AM 533
            .|||:.|..|||:||...|.:....:.....||||:|: .|.|:.:.:...||||:.::|:  ::
  Rat   193 NGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-QEKALMKPVATVGPISVAMDASHPSL 256

  Fly   534 QFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDY-PNFHKTLPYWIVKNSWGPRWGEQGYYRVYR 597
            |||..|:.  ::..||.|:|||||||||||.... .|..|   ||:||||||..||..||.::.:
  Rat   257 QFYSSGIY--YEPNCSSKDLDHGVLVVGYGYEGTDSNKDK---YWLVKNSWGKEWGMDGYIKIAK 316

  Fly   598 G-DNTCGVSEMATSAVL 613
            . :|.||::..|:..::
  Rat   317 DRNNHCGLATAASYPIV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	16/60 (27%)
		Peptidase_C1A	395..611	CDD:239068	103/221 (47%)
Ctsl	NP_037288.1	Inhibitor_I29	29..87	CDD:214853	20/80 (25%)
		Peptidase_C1	114..332	CDD:425470	103/223 (46%)