DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12163 and BC051665

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_954599.2	Gene:	BC051665 / 218275	MGIID:	2682300	Length:	330	Species:	Mus musculus

Alignment Length:	347	Identity:	126/347 - (36%)
Similarity:	182/347 - (52%)	Gaps:	50/347 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 VVQA--RHTRSVE--WAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLK 337
            ||.|  .|..|::  |.|.||    .||                :.|....|.|.| .::..|:|
Mouse    14 VVSAAPAHDPSLDAVWEEWKT----KHR----------------KTYNMNEEAQKR-AVWENNMK 57

  Fly   338 TIEELNANEMGSAKYG----ITEFADMTSSEYKE-RTGLWQRDEAKATGGSAAVVPAYHGELPKE 397
            .| .|:..:....|:|    :..|.|:|::|::| .||.......:.|.....::    |::||.
Mouse    58 MI-GLHNEDYLKGKHGFNLEMNAFGDLTNTEFRELMTGFQSMGHKEMTIFQEPLL----GDVPKS 117

  Fly   398 FDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGL 460
            .|||....||.||:||.||||||||..|::||....|||:|...|||.|:||..:  :..|||||
Mouse   118 VDWRDHGYVTPVKDQGHCGSCWAFSAVGSLEGQIFRKTGKLVPLSEQNLMDCSWSYGNVGCNGGL 182

  Fly   461 MDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPIS 525
            |:.|::.:|:..||:....|.|:|....|.::...|.|.:.|||.:|. :|.|:...:.:.||:|
Mouse   183 MELAFQYVKENRGLDTRESYAYEAWDGPCRYDPKYSAVNITGFVKVPL-SEDALMNAVASVGPVS 246

  Fly   526 IGINA--NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYG-VSDYPNFHKTLPYWIVKNSWGPRW 587
            :||:.  ::.:|||||..  ::..||..||||.||||||| .||      ...||:||||||..|
Mouse   247 VGIDTHHHSFRFYRGGTY--YEPDCSSTNLDHAVLVVGYGEESD------GRKYWLVKNSWGEDW 303

  Fly   588 GEQGYYRVYRG-DNTCGVSEMA 608
            |..||.::.:. ||.||::..|
Mouse   304 GMDGYIKMAKDRDNNCGIATYA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	13/60 (22%)
		Peptidase_C1A	395..611	CDD:239068	96/220 (44%)
BC051665	NP_954599.2	PTZ00203	7..326	CDD:185513	126/347 (36%)
		Inhibitor_I29	29..87	CDD:214853	19/79 (24%)
		Peptidase_C1	114..329	CDD:278538	96/221 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710