DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Y113G7B.15

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_507904.2	Gene:	Y113G7B.15 / 190976	WormBaseID:	WBGene00013764	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	97/362 - (26%)
Similarity:	150/362 - (41%)	Gaps:	70/362 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 HRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNA---NEMGSAKYGITEFADM 360
            |..:.:.| |..|.:...:.|.:.||:..||..|.:|.:.|:||||   .|..:..:|..:|||.
Worm    22 HSQEVLSH-FNNFTMHHKKHYRTPAEKDRRLAHFAKNHQKIQELNAKARREGRNVTFGWNKFADK 85

  Fly   361 TSSEYKERTGLWQRDEAKATGGSAAVVPAY-------------------HGELPKEFDWRQ---- 402
            ...|...|       .:|....:...:|.|                   .|::|..||.|.
Worm    86 NRQELSAR-------NSKIHPKNHTDLPIYKPRHPRGSRNHHNKRSKRQSGDIPDYFDLRDIYVD 143

  Fly   403 -KDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDC-DTTDS-ACNGGLMDNA 464
             ...|..||:|..||.||||:.|...|....:.:......|:||:.|| |:.|: .|.||...|.
Worm   144 GSPVVGPVKDQEQCGCCWAFATTAITEAANTLYSKSFTSLSDQEICDCADSGDTPGCVGGDPRNG 208

  Fly   465 YKAIKDIGGLEYEAEYPYKAKK----NQCHFNRTLSHVQ-----VAGFVDLPKGNETAMQEWLLA 520
            .|.: .:.|...:.:|||:..:    ..|..:...:.:|     |..| |.....|..|:...|.
Worm   209 LKMV-HLRGQSSDGDYPYEEYRANTTGNCVGDEKSTVIQPETLNVYRF-DQDYAEEDIMENLYLN 271

  Fly   521 NGPISIGINANAMQFYRGGVSHPWKALCSKKNLD---------HGVLVVGYGVSDYPNFHKTLPY 576
            :.|.::        ::|.|.:..|......::.|         |.|.:||||.||     ..:||
Worm   272 HIPTAV--------YFRVGENFEWYTSGVLQSEDCYQMTPAEWHSVAIVGYGTSD-----DGVPY 323

  Fly   577 WIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            |:|:|||...||..||.::.||.|.|.:...|.:|::
Worm   324 WLVRNSWNSDWGLHGYVKIRRGVNWCLIESHAATAMI 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	19/59 (32%)
		Peptidase_C1A	395..611	CDD:239068	69/240 (29%)
Y113G7B.15	NP_507904.2	Inhibitor_I29	30..90	CDD:285458	19/59 (32%)
Y113G7B.15	NP_507904.2	Peptidase_C1A	132..358	CDD:239068	69/240 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910