DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Y71H2AR.2

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001367938.1	Gene:	Y71H2AR.2 / 190615	WormBaseID:	WBGene00022189	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	84/241 - (34%)
Similarity:	125/241 - (51%)	Gaps:	35/241 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 PAYHGELPKEF-DWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKT-GELKEFSEQELLDCD 450
            |.:.....:|| |||:|..|..||:||.|.:..||::|.:||.:||..| |.|..||||:|:||:
Worm    75 PIHMDRTTEEFLDWREKGIVGPVKDQGKCNASHAFAITSSIESMYAKATNGTLLSFSEQQLIDCN 139

  Fly   451 TTDSACNGGLMDNAYK------AIKDIG-----GLEYEAEYPYKAKKNQ-CHFNRTLSHVQVAGF 503
                       |..||      |:..||     |:|.||:|||..|.|: |.|:.|.|.:.:...
Worm   140 -----------DQGYKGCEEQFAMNAIGYLATHGIETEADYPYVDKTNEKCTFDSTKSKIHLKKG 193

  Fly   504 VDLPKGNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDY 567
            | :.:|||...:.::...||....:.| .::..|:.|:.:|....|:..:....:::||||:...
Worm   194 V-VAEGNEVLGKVYVTNYGPAFFTMRAPPSLYDYKIGIYNPSIEECTSTHEIRSMVIVGYGIEGE 257

  Fly   568 PNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            ..      |||||.|:|..||||||.::.|..|.|.::  .|.|||
Worm   258 QK------YWIVKGSFGTSWGEQGYMKLARDVNACAMA--TTIAVL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458
		Peptidase_C1A	395..611	CDD:239068	80/230 (35%)
Y71H2AR.2	NP_001367938.1	Peptidase_C1A	84..290	CDD:239068	79/225 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820