DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Y40H7A.10

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_502836.1	Gene:	Y40H7A.10 / 189809	WormBaseID:	WBGene00012747	Length:	343	Species:	Caenorhabditis elegans

Alignment Length:	309	Identity:	94/309 - (30%)
Similarity:	149/309 - (48%)	Gaps:	26/309 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 KVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEYKE 367
            |..:.|..|.|::.|.|.:..|...|..||.:||..:|..|..:.|...|.:.:|:|:|..|:|:
Worm    46 KYTNAFQNFLVKYLREYPNEYEIVKRFTIFSRNLDLVERYNKEDAGKVTYELNDFSDLTEEEWKK 110

  Fly   368 RTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDA---VTQVKNQGSCGSCWAFSVTGNIEG 429
            .....:.|.::.:.....::...:  ||...|||..:.   ||.:|.||.|||||||:....||.
Worm   111 YLMTPKPDHSEKSLKPKTLIDKKN--LPNSVDWRNVNGTNHVTGIKYQGPCGSCWAFATAAAIES 173

  Fly   430 LYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRT 494
            ..::..|.|:..|.|:||||......|.||....|.|..:. .|:.....|||.....:|  ..|
Worm   174 AVSISGGGLQSLSSQQLLDCTVVSDKCGGGEPVEALKYAQS-HGITTAHNYPYYFWTTKC--RET 235

  Fly   495 LSHV-QVAGFVDLPKGNETAMQEWLLANGPISIGIN--ANAMQFYRGGVSHPWKALCSKKNLDHG 556
            :..| :::.:  :...:|..|.:.:..|||:.:..|  .|..:||..|::.  ...|..:. .|.
Worm   236 VPTVARISSW--MKAESEDEMAQIVALNGPMIVCANFATNKNRFYHSGIAE--DPDCGTEP-THA 295

  Fly   557 VLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVS 605
            ::|:|||    |:      |||:||::...|||:||.||.|..|.||::
Worm   296 LIVIGYG----PD------YWILKNTYSKVWGEKGYMRVKRDVNWCGIN 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	18/56 (32%)
		Peptidase_C1A	395..611	CDD:239068	71/217 (33%)
Y40H7A.10	NP_502836.1	Inhibitor_I29	51..108	CDD:285458	18/56 (32%)
Y40H7A.10	NP_502836.1	Peptidase_C1A	136..336	CDD:239068	71/217 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810