Protein Alignment CtsF and cpr-2

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_507186.3
• Gene: cpr-2 / 185355
• WormBaseID: WBGene00000782
• Length: 326
• Species: Caenorhabditis elegans
• Alignment Length: 310
• Identity: 71/310 - (22%)
• Similarity: 125/310 - (40%)
• Gaps: 69/310 - (22%)

  Fly   339 IEELN--ANEMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFD-- 399
            ::.:|  |:...:..|.:|.....|.|.:::....:. ||.:||.....:     ...|..||
 Worm    32 VDHINSAASTFQTENYAVTHEKMHTRSMHEKFNAPFP-DEFRATEREFVL-----DATPLNFDAR 90

  Fly   400 --WRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKE--FSEQELLDC--DTTDSACNG 458
              |.|..::..::.|.:||||||||....|.....:.:...::  .|..:||.|  .:....|:|
 Worm    91 TRWPQCKSMKLIREQSNCGSCWAFSTAEVISDRTCIASNGTQQPIISPTDLLTCCGMSCGEGCDG 155

  Fly   459 GLMDNAYKAIK------DIGGLEYEA----EYPYK-AKKNQC--------------HFNRTLSHV 498
            |.   .|:|.:      .:.|.:|..    .||.: ...:.|              .:..|.::
 Worm   156 GF---PYRAFQWWARRGVVTGGDYLGTGCKPYPIRPCNSDNCVNLQTPPCRLSCQPGYRTTYTN- 216

  Fly   499 QVAGFVDLPKGNE--------TAMQEWLLANGP-ISIGINANAMQFYRGGVSHPWKALCSKKNLD 554
                  |...||.        .|:|..:..||| ::..|.....:.|:.|:   ::.:..:....
 Worm   217 ------DKNYGNSAYPVPRTVAAIQADIYYNGPVVAAFIVYEDFEKYKSGI---YRHIAGRSKGG 272

  Fly   555 HGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGV 604
            |.|.::|:|.      .:..|||:..||||.:|||.|.:|:.||.:.||:
 Worm   273 HAVKLIGWGT------ERGTPYWLAVNSWGSQWGESGTFRILRGVDECGI 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	6/27 (22%)
		Peptidase_C1A	395..611	CDD:239068	61/252 (24%)
cpr-2	NP_507186.3	Peptidase_C1A_CathepsinB	84..323	CDD:239111	61/252 (24%)