DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and F15D4.4

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_496805.3	Gene:	F15D4.4 / 184530	WormBaseID:	WBGene00008861	Length:	608	Species:	Caenorhabditis elegans

Alignment Length:	315	Identity:	87/315 - (27%)
Similarity:	137/315 - (43%)	Gaps:	58/315 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 STAERQM-RLRIFRQNLKTIEELN-ANEMGSAKYGIT--EFADMTSSEYKERTGLWQRDEAKATG 381
            |||:..: |..::.:..|.::|.| ..|:|.:.|.::  :|:.....|....|     ....|..
Worm   146 STAKEGLKRFNVYSKVKKEVDEHNIMYELGMSSYKMSTNQFSVALDGEVAPLT-----LNLDALT 205

  Fly   382 GSAAVVPAYHGELPKE-----FDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEF 441
            .:|.|:||......|.     .|||  ..:..:.:|.:||.|||||:...||..:|::.......
Worm   206 PTATVIPATISSRKKRDTEPTVDWR--PFLKPILDQSTCGGCWAFSMISMIESFFAIQGYNTSSL 268

  Fly   442 SEQELLDCDT-TDS-------ACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQC---HFNRTL 495
            |.|:||.||| .||       .|.||....|...: ::......:..|:..:...|   .|...:
Worm   269 SVQQLLTCDTKVDSTYGLANVGCKGGYFQIAGSYL-EVSAARDASLIPFDLEDTSCDSSFFPPVV 332

  Fly   496 SHVQV--AGFVDLPKGNETAMQ--------EWLLANGPISIGINANA-MQFYRGGVSHPWKALCS 549
            ..:.:  .|::   .||.||.|        |..:..|||::|:.|.. :..|..||   :...|.
Worm   333 PTILLFDDGYI---SGNFTAAQLITMEQNIEDKVRKGPIAVGMAAGPDIYKYSEGV---YDGDCG 391

  Fly   550 KKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYR--GDNTC 602
             ..::|.|::||:          |..|||::||||..|||.||:||.|  |.:.|
Worm   392 -TIINHAVVIVGF----------TDDYWIIRNSWGASWGEAGYFRVKRTPGKDPC 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	11/47 (23%)
		Peptidase_C1A	395..611	CDD:239068	69/237 (29%)
F15D4.4	NP_496805.3	Inhibitor_I29	<146..187	CDD:214853	10/40 (25%)
F15D4.4	NP_496805.3	Peptidase_C1A	227..442	CDD:239068	68/229 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810