DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and tag-329

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_505458.1	Gene:	tag-329 / 183677	WormBaseID:	WBGene00008231	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	331	Identity:	93/331 - (28%)
Similarity:	149/331 - (45%)	Gaps:	36/331 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 DKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELN--ANEMG-SAKYGITEFADMTSS 363
            :|:...|..|.|::.|.|....|::.|.:.|......:.::|  |.:.| ..||||.:|:|::.
Worm    41 EKLYKEFEDFIVKYKRNYKDEIEKKFRFQQFVATHNRVGKMNKAAKKAGHDTKYGINKFSDLSK- 104

  Fly   364 EYKERTGLWQRDEAKATGGSAAVVPAYHGE----------LPKEFDWRQKDA-----VTQVKNQG 413
              ||..|::.:........:   ||.::.:          |||.||.|.|..     :..:|.|.
Worm   105 --KEIHGMYSKFGPPKNNTN---VPKFNLKNLRVKRQMEGLPKTFDLRNKKVGGHYIIGPIKTQD 164

  Fly   414 SCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDS-ACNGGLMDNAYKAIKDIGGLEYE 477
            ||..||.|:.|...|....|...:....||||:.||..... .||||...:..:.||:: ||...
Worm   165 SCACCWGFAATAVAEAALTVHLKKAMNLSEQEVCDCAPKHGPGCNGGDPVDGLEYIKEM-GLTGG 228

  Fly   478 AEYPYKAKKN----QCH---FNRTLSHVQVAGFVDLPKGNETAMQEWL-LANGPISIGINANA-M 533
            .|||:...::    :|.   ::|.|:.:::..:...|...|..|...| |.|.|||:.....| :
Worm   229 KEYPFNVNRSTQLGRCESEKYDRELNPLELDYYAIDPFNAEYQMTHHLYLLNLPISVAFRTGASL 293

  Fly   534 QFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG 598
            ..|..|:.........|....|...:||||.:. .:..:|:.|||.:|||...||:.||.|:.||
Worm   294 SSYLSGILELADCDDEKGGHWHSGAIVGYGTTK-NSAGRTVDYWIFRNSWWTDWGDDGYARIVRG 357

  Fly   599 DNTCGV 604
            ::.|.:
Worm   358 EDWCSI 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/59 (29%)
		Peptidase_C1A	395..611	CDD:239068	69/225 (31%)
tag-329	NP_505458.1	Inhibitor_I29	47..106	CDD:214853	17/61 (28%)
tag-329	NP_505458.1	Peptidase_C1A	141..368	CDD:239068	69/225 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910