DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and cpl-1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001256718.1	Gene:	cpl-1 / 180111	WormBaseID:	WBGene00000776	Length:	337	Species:	Caenorhabditis elegans

Alignment Length:	347	Identity:	133/347 - (38%)
Similarity:	195/347 - (56%)	Gaps:	43/347 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 VVQARHTRSVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEE 341
            |..|:.:|.:|.|.:|               :..::..|.:.| |.:|.|..:..|.:|:..||.
Worm    16 VNSAKLSRQIESAIEK---------------WDDYKEDFDKEY-SESEEQTYMEAFVKNMIHIEN 64

  Fly   342 LNA-NEMGSAKY--GITEFADMTSSEYKERTGLWQR--DEAKATGGSAAVVPAYHGELPKEFDWR 401
            .|. :.:|...:  |:...||:..|:|::..| ::|  .:::....|:.:.| ::.::|.|.|||
Worm    65 HNRDHRLGRKTFEMGLNHIADLPFSQYRKLNG-YRRLFGDSRIKNSSSFLAP-FNVQVPDEVDWR 127

  Fly   402 QKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNA 464
            ....||.|||||.||||||||.||.:||.:|.|.|:|...|||.|:||.|.  :..|||||||.|
Worm   128 DTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQA 192

  Fly   465 YKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGIN 529
            ::.|:|..|::.|..||||.:..:||||:........|:||.|:|:|..::..:...|||||.|:
Worm   193 FEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAID 257

  Fly   530 A--NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLP----YWIVKNSWGPRWG 588
            |  .:.|.|:.||.:..:  ||.:.||||||:||||         |.|    |||||||||..||
Worm   258 AGHRSFQLYKKGVYYDEE--CSSEELDHGVLLVGYG---------TDPEHGDYWIVKNSWGAGWG 311

  Fly   589 EQGYYRVYRG-DNTCGVSEMAT 609
            |:||.|:.|. :|.|||:..|:
Worm   312 EKGYIRIARNRNNHCGVATKAS 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	15/59 (25%)
		Peptidase_C1A	395..611	CDD:239068	107/224 (48%)
cpl-1	NP_001256718.1	Inhibitor_I29	32..91	CDD:369782	15/59 (25%)
cpl-1	NP_001256718.1	Peptidase_C1	120..335	CDD:365882	107/225 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810