DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and F32H5.1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_506310.1	Gene:	F32H5.1 / 179815	WormBaseID:	WBGene00009347	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	368	Identity:	69/368 - (18%)
Similarity:	110/368 - (29%)	Gaps:	169/368 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 ADMTSSEYKERTGLWQ-----------------------RDE-AKATGGSAAVVPAYHGELPKEF 398
            :|:||...|::. ||:                       .|| ::.||....:|     ::|..|
Worm    38 SDLTSYVNKKQK-LWKAETSRMTFQEKMARAKSIKFIKSNDEVSEKTGNDNVLV-----DIPSSF 96

  Fly   399 DWRQK----DAVTQVKNQGSCGS--------------CWAFSVTGNIEGLYAVKTGELKEFSEQE 445
            |.|||    ..:..|::|..|||              |.|.:.|.|            ...|.|:
Worm    97 DSRQKWPSCSQIGAVRDQSDCGSAAHLVAVEIASDRTCIASNGTFN------------WPLSAQD 149

  Fly   446 LLDCDT-------------------------TDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAK 485
            .|.|..                         |...|.||..::.:       |.:..:.||...|
Worm   150 PLSCCVGLMSICGDGWGCDGSWPKDILKWWQTHGLCTGGNYNDQF-------GCKPYSIYPCDKK 207

  Fly   486 --------------------------------KNQCHFNRTLSHVQVAGFVDLPKGNE-TAMQEW 517
                                            |...||.:  :|..|        |.: |.:|..
Worm   208 YANGTTSVPCPGYHTPTCEEHCTSNITWPIAYKQDKHFGK--AHYNV--------GKKMTDIQIE 262

  Fly   518 LLANGPI-------------SIGINANAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPN 569
            ::.|||:             ..||..:......||:.               ..::|:||.:
Worm   263 IMTNGPVIASFIIYDDFWDYKTGIYVHTAGDQEGGMD---------------TKIIGWGVDN--- 309

  Fly   570 FHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAV 612
               .:|||:..:.||..:||.|:.|..||.|...:.....:|:
Worm   310 ---GVPYWLCVHQWGTDFGENGFVRFLRGVNEVNIEHQVLAAL 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	3/6 (50%)
		Peptidase_C1A	395..611	CDD:239068	57/304 (19%)
F32H5.1	NP_506310.1	Peptidase_C1A_CathepsinB	93..348	CDD:239111	57/304 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810