DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12163 and cpr-9

DIOPT Version :9

Sequence 1:NP_730901.1 Gene:CG12163 / 40628 FlyBaseID:FBgn0260462 Length:614 Species:Drosophila melanogaster
Sequence 2:NP_001369965.1 Gene:cpr-9 / 179645 WormBaseID:WBGene00010204 Length:351 Species:Caenorhabditis elegans


Alignment Length:352 Identity:83/352 - (23%)
Similarity:131/352 - (37%) Gaps:102/352 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   302 DKVDHLFYKFQVRFG---RRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITE---FADM 360
            |.|:.:...|:...|   ..|..|.::|:                   ||:....|.|   ..:|
 Worm    42 DYVNKVQTSFKAELGSYFSSYPDTIKKQL-------------------MGAKMVEIPEEYRVFEM 87

  Fly   361 TSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFD----WRQKDAVTQVKNQGSCGSCWAF 421
            |..|.::                |||        |..||    |....:::::::|.|||||||.
 Worm    88 THPEVED----------------AAV--------PDSFDSRTAWPNCPSISKIRDQSSCGSCWAV 128

  Fly   422 SVTGNIEGLYAVKTG--ELKEFSEQELLDC--DTTDSACNGGLMDNAYKAIKDIG---GLEYEAE 479
            |....|.....:.:.  .:...|..::..|  ....:.||||....|::.....|   |..|:.:
 Worm   129 SAAETISDRICIASNAKTILSISADDINACCGMVCGNGCNGGYPIEAWRHYVKKGYVTGGSYQDK 193

  Fly   480 -----YPY---KAKKNQCHFNRTLSHVQ---------VAGFV-----DLPKGNE--------TAM 514
                 |||   :...|..|:....|::.         .||:.     ||..|..        ..:
 Worm   194 TGCKPYPYPPCEHHVNGTHYKPCPSNMYPTDKCERSCQAGYALTYQQDLHFGQSAYAVSKKAAEI 258

  Fly   515 QEWLLANGPISIGINA-NAMQFYRGGV-SHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYW 577
            |:.::.:||:.:.... ...:.|.||| .|...|...    .|.|.::|:||.:      ..|||
 Worm   259 QKEIMTHGPVEVAFTVYEDFEHYSGGVYVHTAGASLG----GHAVKMLGWGVDN------GTPYW 313

  Fly   578 IVKNSWGPRWGEQGYYRVYRGDNTCGV 604
            :..|||...|||.||:|:.||.|.||:
 Worm   314 LCANSWNEDWGENGYFRIIRGVNECGI 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12163NP_730901.1 CY 194..272 CDD:298856
Inhibitor_I29 308..365 CDD:285458 11/62 (18%)
Peptidase_C1A 395..611 CDD:239068 66/253 (26%)
cpr-9NP_001369965.1 Propeptide_C1 38..74 CDD:400445 9/50 (18%)
Peptidase_C1A_CathepsinB 98..338 CDD:239111 64/249 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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