Protein Alignment CtsF and cpr-1

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_506002.2
• Gene: cpr-1 / 179637
• WormBaseID: WBGene00000781
• Length: 329
• Species: Caenorhabditis elegans
• Alignment Length: 302
• Identity: 83/302 - (27%)
• Similarity: 132/302 - (43%)
• Gaps: 65/302 - (21%)

  Fly   355 TEFADMTSSE--YKERTGLW---QRDEAKATGGSAAVVPAYHGELPKEFD----WRQKDAVTQVK 410
            ||..::|..|  :|...|.:   ..||.:||  ...||.|   .:|..||    |.:..::..::
 Worm    46 TEHVEITEEEMKFKLMDGKYAAAHSDEIRAT--EQEVVLA---SVPATFDSRTQWSECKSIKLIR 105

  Fly   411 NQGSCGSCWAFSVTGNIEGLYAVKTGELKE--FSEQELLDC--DTTDSACNGGLMDNAYKAIK-- 469
            :|.:|||||||.....|.....::|...::  .|..:||.|  .:..:.|.||.   ..:|::
 Worm   106 DQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSCCGSSCGNGCEGGY---PIQALRWW 167

  Fly   470 DIGGLEYEAEY------PY---KAKKNQCHFNRTLS-----------------HVQVAGFVDLPK 508
            |..|:....:|      ||   ......|..::|.|                 |..|:.:. :||
 Worm   168 DSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKDKHFGVSAYA-VPK 231

  Fly   509 GNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHK 572
             |..::|..:.||||:....:. .....|:.||   :|....|....|.:.::|:|.      ..
 Worm   232 -NAASIQAEIYANGPVEAAFSVYEDFYKYKSGV---YKHTAGKYLGGHAIKIIGWGT------ES 286

  Fly   573 TLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVLA 614
            ..|||:|.||||..|||.|::::||||:.||:.    |||:|
 Worm   287 GSPYWLVANSWGVNWGESGFFKIYRGDDQCGIE----SAVVA 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	4/11 (36%)
		Peptidase_C1A	395..611	CDD:239068	66/252 (26%)
cpr-1	NP_506002.2	Peptidase_C1A_CathepsinB	86..325	CDD:239111	70/257 (27%)