DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and cpr-1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_506002.2	Gene:	cpr-1 / 179637	WormBaseID:	WBGene00000781	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	83/302 - (27%)
Similarity:	132/302 - (43%)	Gaps:	65/302 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 TEFADMTSSE--YKERTGLW---QRDEAKATGGSAAVVPAYHGELPKEFD----WRQKDAVTQVK 410
            ||..::|..|  :|...|.:   ..||.:||  ...||.|   .:|..||    |.:..::..::
Worm    46 TEHVEITEEEMKFKLMDGKYAAAHSDEIRAT--EQEVVLA---SVPATFDSRTQWSECKSIKLIR 105

  Fly   411 NQGSCGSCWAFSVTGNIEGLYAVKTGELKE--FSEQELLDC--DTTDSACNGGLMDNAYKAIK-- 469
            :|.:|||||||.....|.....::|...::  .|..:||.|  .:..:.|.||.   ..:|::
Worm   106 DQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSCCGSSCGNGCEGGY---PIQALRWW 167

  Fly   470 DIGGLEYEAEY------PY---KAKKNQCHFNRTLS-----------------HVQVAGFVDLPK 508
            |..|:....:|      ||   ......|..::|.|                 |..|:.:. :||
Worm   168 DSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKDKHFGVSAYA-VPK 231

  Fly   509 GNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHK 572
             |..::|..:.||||:....:. .....|:.||   :|....|....|.:.::|:|.      ..
Worm   232 -NAASIQAEIYANGPVEAAFSVYEDFYKYKSGV---YKHTAGKYLGGHAIKIIGWGT------ES 286

  Fly   573 TLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVLA 614
            ..|||:|.||||..|||.|::::||||:.||:.    |||:|
Worm   287 GSPYWLVANSWGVNWGESGFFKIYRGDDQCGIE----SAVVA 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	4/11 (36%)
		Peptidase_C1A	395..611	CDD:239068	66/252 (26%)
cpr-1	NP_506002.2	Peptidase_C1A_CathepsinB	86..325	CDD:239111	70/257 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810