DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and cpz-1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_491023.2	Gene:	cpz-1 / 171829	WormBaseID:	WBGene00000788	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	70/230 - (30%)
Similarity:	108/230 - (46%)	Gaps:	41/230 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 ELPKEFDWRQKDAVTQV---KNQ---GSCGSCWAFSVTGNIEGLYAVKTGEL---KEFSEQELLD 448
            :|||.:|||..:.:...   :||   ..|||||||..|..:.....:|....   ...|.||::|
Worm    64 DLPKTWDWRDANGINYASADRNQHIPQYCGSCWAFGATSALADRINIKRKNAWPQAYLSVQEVID 128

  Fly   449 CDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCH-FNR---------------TLSH 497
            |....:...||.....||...: .|:.:|....|:|:..:|. :||               ||..
Worm   129 CSGAGTCVMGGEPGGVYKYAHE-HGIPHETCNNYQARDGKCDPYNRCGSCWPGECFSIKNYTLYK 192

  Fly   498 VQVAGFVDLPKGNETAMQEWLLANGPISIGINA-NAMQFYRGGVSHPWKALCSKKNLDHGVLVVG 561
            |...|.|   .|.| .|:..:...|||:.||.| .|.:.|.||:   :|.: :.:::||.:.|.|
Worm   193 VSEYGTV---HGYE-KMKAEIYHKGPIACGIAATKAFETYAGGI---YKEV-TDEDIDHIISVHG 249

  Fly   562 YGVSDYPNFHKT-LPYWIVKNSWGPRWGEQGYYRV 595
            :||.     |:: :.|||.:||||..|||.|::::
Worm   250 WGVD-----HESGVEYWIGRNSWGEPWGEHGWFKI 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458
		Peptidase_C1A	395..611	CDD:239068	69/228 (30%)
cpz-1	NP_491023.2	Peptidase_C1A_CathepsinX	65..305	CDD:239149	70/229 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810