Protein Alignment CG12163 and Y65B4A.2

DIOPT Version :9

• Sequence 1: NP_730901.1
• Gene: CG12163 / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001293246.1
• Gene: Y65B4A.2 / 171655
• WormBaseID: WBGene00022026
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 86/390 - (22%)
• Similarity: 141/390 - (36%)
• Gaps: 126/390 - (32%)

  Fly   308 FYKFQVRFGRRYVSTA------ERQMRLRIFRQ---NLKTIEELNANEMG--SAKYGITEFADMT 361
            ||.:     ||||:.|      :..:| ::.||   :.:|..:...|:.|  :..||.....:.|
 Worm    74 FYLY-----RRYVTDANDKRDNDEYLR-KLVRQVNDSPETTWKAKFNKFGVKNRSYGFKYTRNQT 132

  Fly   362 S-SEYKER------TGLWQR--DEAKATGGSAAVVPAYHGELPKEFDWRQK----DAVTQVKNQG 413
            : .||.|:      :...:|  ||.:....|         ::||.||.|||    .:::.|.|||
 Worm   133 AVEEYVEQIRKFFESDAMKRHLDELENFNSS---------DVPKNFDARQKWPNCPSISNVPNQG 188

  Fly   414 SCGSCWAFSVTGNIEGLYAV-KTGELKE-FSEQELLDCDTTDSACNGGLMDNAYKAIK------- 469
            .||||:|.:..|.......: ..|..|. .||::::.|.:....|.||   :..||:.
 Worm   189 GCGSCFAVAAAGVASDRACIHSNGTFKSLLSEEDIIGCCSVCGNCYGG---DPLKALTYWVNQGL 250

  Fly   470 DIGGLE--------------------YEAE-------------YPYKAKKNQCHFNRTLSHVQVA 501
            ..||.:                    :|||             |..|.:::: ||......:...
 Worm   251 VTGGRDGCRPYSFDLSCGVPCSPATFFEAEEKRTCMKRCQNIYYQQKYEEDK-HFATFAYSMYPR 314

  Fly   502 GFVDLPKGNETA-------------------------MQEWLLANGPISIGINA-NAMQFYRGGV 540
            .....|.|.|..                         :::.:|..||.::.... .....|..||
 Worm   315 SMTVSPDGKERVKVPTIIGHFNDKKTEKLNVTEYRDIIKKEILLYGPTTMAFPVPEEFLHYSSGV 379

  Fly   541 SHPWKALCSKKNLD------HGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGD 599
            ..|:..    ...|      |.|.::|:|.|| ...|    ||:..||:|..||:.|.:::...|
 Worm   380 FRPYPT----DGFDDRIVYWHVVRLIGWGESD-DGTH----YWLAVNSFGNHWGDNGLFKINTDD 435

  Fly   600  599
             Worm   436  435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	16/68 (24%)
		Peptidase_C1A	395..611	CDD:239068	63/283 (22%)
Y65B4A.2	NP_001293246.1	Peptidase_C1A_CathepsinB	166..444	CDD:239111	63/283 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810