DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and Kng1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001095881.1	Gene:	Kng1 / 16644	MGIID:	1097705	Length:	661	Species:	Mus musculus

Alignment Length:	403	Identity:	72/403 - (17%)
Similarity:	115/403 - (28%)	Gaps:	187/403 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DAESTESSETTTDQAVSE------------------------PPITLVHVLNPGEREYLSPNLIG 74
            |||...:.|.|......|                        |.|..||.::..     ||:|..
Mouse    98 DAEEAATGECTATVGKRENEFFIVTQTCKIAPSKAPILKAYFPCIGCVHAISTD-----SPDLEP 157

  Fly    75 VQNIAMTFLPLSMNFVN-------------IIDAFREITAGVRYEILLNALDTKAIQPAEADIVC 126
            |       |..|:...|             :..|.|::.||:.::|...
Mouse   158 V-------LKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYT---------------- 199

  Fly   127 RLVILEKPWLRTQWGDKHRELVTSNCTDPAVNSVAGDPAE---------KARL---LNEKYVHRS 179
                                :|.:||:.....|:.||...         :..|   :|.|..:.|
Mouse   200 --------------------IVQTNCSKERFPSLHGDCVALPNGDDGECRGNLFMDINNKIANFS 244

  Fly   180 RR----SANDIL----------GRHKPYDEEAAKAQLQKSLDKLTAGEGPH---YKIVKVYSASR 227
            :.    |.:|::          .|..|.|....|..|..|:.:|.| |..|   |||..|..|:.
Mouse   245 QSCTLYSGDDLVEALPKPCPGCPRDIPVDSPELKEVLGHSIAQLNA-ENDHPFYYKIDTVKKATS 308

  Fly   228 QVDSGILTRID-------------ADLIDGSEEQH-----RCIVDIWTKVWVRKDEHEI--TFKC 272
            ||.:|....|:             .:|.:..|.:|     .|..:::.:.|    |:::  |.||
Mouse   309 QVVAGTKYVIEFIARETKCSKESNTELAEDCEIKHLGQSLDCNANVYMRPW----ENKVVPTVKC 369

  Fly   273 ------------------RNQPVVQARHTRSVE------------------------WAEK---- 291
                              |:..|.:.:..|:|.                        |..:
Mouse   370 QALDMTEMARRPPGFSPFRSVTVQETKEGRTVSPPYIAREQEERDAETEQGPTHGHGWLHEKQIK 434

  Fly   292 --KTHKKHSHRFD 302
              |.|:.|.|..|
Mouse   435 ANKNHRGHKHGHD 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856	24/100 (24%)
		Inhibitor_I29	308..365	CDD:285458
		Peptidase_C1A	395..611	CDD:239068
Kng1	NP_001095881.1	CY	23..126	CDD:214484	6/27 (22%)
		CY	141..248	CDD:214484	25/154 (16%)
		CY	263..370	CDD:214484	27/111 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..471		6/43 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	485..583
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	626..661
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910