Protein Alignment CtsF and LOC1273088

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_061503275.1
• Gene: LOC1273088 / 1273088
• VectorBaseID: AGAMI1_013370
• Length: 1846
• Species: Anopheles gambiae
• Alignment Length: 651
• Identity: 254/651 - (39%)
• Similarity: 349/651 - (53%)
• Gaps: 134/651 - (20%)

  Fly    19 AGEELAEERAGQAQGDAESTESSETTTDQAVSEPPITLVHVLNPGEREYLSPNLIGVQNIAMTFL 83
            ||......|.....|.:.|....|....:.:..  :..:.|.:.|.:|
Mosquito  1275 AGPAKVRTRRSVVPGGSRSLSQDELAAAEHLER--VDKILVSSGGSKE----------------- 1320

  Fly    84 PLSMNFVNIIDAFREITAGVRYEILLNALDTKAIQPAEADI-----VCRLVILEKPWLRTQWGDK 143
              |.| ..|:....:|.:|..|:..:           |.|:     :|:|...|:|||
Mosquito  1321 --SSN-ARIVSGTVQIVSGKLYKYAV-----------EFDVDGSSKLCKLSSWERPWL------- 1364

  Fly   144 HRELVTSNCTDPAVNSVAGDPAEKARLL----NEKYVHRSRRSANDILGRHKPYDEEAAKAQLQK 204
                            |..||.|..:..    :||...|.||.|.    :....:|..|:....|
Mosquito  1365 ----------------VKKDPTEAYKYTVSCPSEKAAGRQRRHAK----KAGSSNELTAEELKDK 1409

  Fly   205 S-LDKLTAG-------EGPHYKIVKVYSASRQVDSGILTRI------DADLIDGSEEQHRCIVDI 255
            | ::::.||       ....|...::.:.|.|..:|.|.:.      ::|::        |.:.|
Mosquito  1410 SHVERIRAGMVSYNSERSKAYNEFEILAGSTQQVAGSLYKYTFRVTSESDIV--------CKISI 1466

  Fly   256 WTKVWVR-KDEHEITFKCRNQ--------------------------PVVQARHTRSVEWAEKKT 293
            |.:||:. :|:.:...||...                          |.|:.|..||:: .:...
Mosquito  1467 WERVWLESQDQRKYNVKCTGDDDTEQQPDIKSPQQPDAPAPTPVTTAPAVKRRSVRSLK-IDDDA 1530

  Fly   294 HKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFA 358
            |         |..:|.||:....|:|.|:.|.:||..|||.||..||:||..|.|:||||:|:||
Mosquito  1531 H---------VRRMFDKFRHHHRRQYASSMEHEMRFNIFRNNLFKIEQLNKFERGTAKYGVTKFA 1586

  Fly   359 DMTSSEYKERTGLW--QRDEAKATGGSAAVVP--AYHGELPKEFDWRQKDAVTQVKNQGSCGSCW 419
            |||.:||:..|||.  :.|.|...|...|...  |..|:||:.||||...|||:|||||||||||
Mosquito  1587 DMTVAEYRAHTGLVVPKHDRANHVGNRVASEEDVAGVGDLPRSFDWRDHGAVTEVKNQGSCGSCW 1651

  Fly   420 AFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKA 484
            |||..||:|||:.:||.:|:.:|||||:|||..|:.|.||.||:|:|||:.:||||.|.:|||:|
Mosquito  1652 AFSAVGNVEGLHQIKTKKLESYSEQELIDCDKVDNGCGGGYMDDAFKAIEQLGGLELENDYPYEA 1716

  Fly   485 K-KNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALC 548
            | :..|||||:||||||.|.||:|| |||.:.::|:.||||:||:|||||||||||:||||..||
Mosquito  1717 KAQKSCHFNRSLSHVQVKGAVDMPK-NETYIAQYLIKNGPIAIGLNANAMQFYRGGISHPWHPLC 1780

  Fly   549 SKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            :.|::|||||:||||:.:||.|:|||||||:|||||||||||||||:|||||:|||||||:||:|
Mosquito  1781 NHKSIDHGVLIVGYGIKEYPMFNKTLPYWIIKNSWGPRWGEQGYYRIYRGDNSCGVSEMASSAIL 1845

  Fly   614 A 614
            |
Mosquito  1846 A 1846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	30/56 (54%)
		Peptidase_C1A	395..611	CDD:239068	148/216 (69%)
LOC1273088	XP_061503275.1	None