Protein Alignment CtsF and Cts3

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_081182.2
• Gene: Cts3 / 117066
• MGIID: 2151929
• Length: 332
• Species: Mus musculus
• Alignment Length: 312
• Identity: 107/312 - (34%)
• Similarity: 166/312 - (53%)
• Gaps: 18/312 - (5%)

  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGIT----EFADMTSSE 364
            :|..:.|:::::|:.|....|.|.| .::.:|:|.| :|:..|.|..|:|.|    .|.|||..|
Mouse    25 LDAEWQKWKIKYGKTYSLEEEGQKR-AVWEENMKKI-KLHNGENGLGKHGFTMEMNAFGDMTLEE 87

  Fly   365 Y-KERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIE 428
            : ||...:    .........:|.......|||..:|:::..||.|:.|.:|.||||.||||.||
Mouse    88 FRKEMIEI----PVPTVKKGKSVQKRLSVNLPKFINWKKRGYVTPVRTQIACNSCWAISVTGAIE 148

  Fly   429 GLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNR 493
            |....|||:|...|.|.|:|| ...|.|:.|.:.:::|.:.:.||||.||.|||:.|:..|.:|.
Mouse   149 GQMFRKTGQLIPLSVQNLVDC-VDGSGCHAGSVLDSFKYLMEKGGLESEATYPYEDKQGSCRYNP 212

  Fly   494 TLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGGVSHPWKALCSKKNLDHG 556
            ..|...:.||..:| .||..:...:.:.||||:.|:|  .:..||:.|:.:......|...|.|.
Mouse   213 ENSTASITGFEFIP-NNEVDLMSAVASLGPISVVIDAWHESFLFYKRGIYYEPNCNNSLFALRHA 276

  Fly   557 VLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGD-NTCGVSEM 607
            ||:||||.....:  :...|||:|||.|.:||.:||.::.:.. |.||::.:
Mouse   277 VLLVGYGFIGRES--EGRKYWIIKNSLGTKWGYKGYMKIAKDQGNHCGIASL 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	19/60 (32%)
		Peptidase_C1A	395..611	CDD:239068	82/216 (38%)
Cts3	NP_081182.2	Inhibitor_I29	29..87	CDD:214853	19/59 (32%)
		Peptidase_C1A	115..330	CDD:239068	82/216 (38%)