DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12163 and LOC105947118

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_017948891.2	Gene:	LOC105947118 / 105947118	-ID:	-	Length:	328	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	113/318 - (35%)
Similarity:	161/318 - (50%)	Gaps:	40/318 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 FYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSE-------- 364
            |..|..:|.:.|.|..|...|..||::||:..:.|...|.|:|:||||:|:|:|..|
Frog    27 FENFIAQFNKTYASKEEFHRRFAIFQKNLEEAKRLQREERGTAQYGITKFSDLTDEEFLRCRPDH 91

  Fly   365 ---YKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQG-SCGSCWAFSVTG 425
               ::.:|.|.|..|..|        |.      |..|||:|..::..|||| ||.||:||:..|
Frog    92 RAYFESQTLLRQVTEENA--------PV------KTCDWRKKGVISVPKNQGPSCLSCYAFAAVG 142

  Fly   426 NIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCH 490
            |||..:.: .|..|..|.|:|:||  :...|.||...||:..:..||||..|..|.|..||:.|.
Frog   143 NIEAQWGI-WGSPKNLSVQQLVDC--SKCGCQGGYTWNAFMTVIKIGGLTNEKNYKYTGKKSTCK 204

  Fly   491 FNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALCSKKNLDH 555
            .| ......:..||.|.: |||.:...:...|.:::.||...::.|:.||..|....|. .|:||
Frog   205 TN-LKPEATIQDFVILQR-NETVICSHVSYKGTVTVAINQTLLKQYQKGVIDPHPEKCD-NNVDH 266

  Fly   556 GVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            .||:||        |.:...|||:|||||..|||.|::|:..|.|.||::|...||::
Frog   267 AVLIVG--------FSREKKYWILKNSWGNDWGENGFFRLRLGSNACGIAEYPASAIV 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	23/67 (34%)
		Peptidase_C1A	395..611	CDD:239068	82/216 (38%)
LOC105947118	XP_017948891.2	Inhibitor_I29	27..83	CDD:214853	22/55 (40%)
LOC105947118	XP_017948891.2	Peptidase_C1A	115..314	CDD:239068	81/212 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I10947
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010